Shivering thermogenesis in humans: Origin, contribution and metabolic requirement

F Haman, DP Blondin - Temperature, 2017 - Taylor & Francis
As endotherms, humans exposed to a compensable cold environment rely on an increase in
thermogenic rate to counteract heat lost to the environment, thereby maintaining a stable …

Shivering and nonshivering thermogenesis in skeletal muscles

DP Blondin, F Haman - Handbook of clinical neurology, 2018 - Elsevier
Humans have inherited complex neural circuits which drive behavioral, somatic, and
autonomic thermoregulatory responses to defend their body temperature. While they are …

Seven days of cold acclimation substantially reduces shivering intensity and increases nonshivering thermogenesis in adult humans

K Gordon, DP Blondin, BJ Friesen… - Journal of Applied …, 2019 - journals.physiology.org
Daily compensable cold exposure in humans reduces shivering by~ 20% without changing
total heat production, partly by increasing brown adipose tissue thermogenic capacity and …

Maintaining thermogenesis in cold exposed humans: relying on multiple metabolic pathways

DP Blondin, HC Tingelstad, O L. Mantha… - Comprehensive …, 2011 - Wiley Online Library
In cold exposed humans, increasing thermogenic rate is essential to prevent decreases in
core temperature. This review describes the metabolic requirements of thermogenic …

Thermoregulatory thermogenesis in humans during cold stress

I Jacobs, L Martineau, AL Vallerand - Exercise and sport sciences …, 1994 - journals.lww.com
Given that a large proportion of our country's geography lies at latitudes where cold
exposure is a fact of life, strategies for survival and/or rescue of victims exposed to …

Shivering in the cold: from mechanisms of fuel selection to survival

F Haman - Journal of Applied Physiology, 2006 - journals.physiology.org
In cold-exposed adult humans, significant or lethal decreases in body temperature are
delayed by reducing heat loss via peripheral vasoconstriction and by increasing rates of …

Four‐week cold acclimation in adult humans shifts uncoupling thermogenesis from skeletal muscles to brown adipose tissue

DP Blondin, A Daoud, T Taylor… - The Journal of …, 2017 - Wiley Online Library
Key points Muscle‐derived thermogenesis during acute cold exposure in humans consists
of a combination of cold‐induced increases in skeletal muscle proton leak and shivering …

Exertion-induced fatigue and thermoregulation in the cold

AJ Young, JW Castellani - … Biochemistry and Physiology Part A: Molecular …, 2001 - Elsevier
Cold exposure facilitates body heat loss which can reduce body temperature, unless
mitigated by enhanced heat conservation or increased heat production. When behavioral …

Cold-induced thermoregulation and biological aging

M Florez-Duquet, RB McDONALD - Physiological reviews, 1998 - journals.physiology.org
Florez-Duquet, Maria, and Roger B. McDonald. Cold-Induced Thermoregulation and
Biological Aging. Physiol. Rev. 78: 339–358, 1998.—Aging is associated with diminished …

Fuel selection during intense shivering in humans: EMG pattern reflects carbohydrate oxidation

F Haman, SR Legault, JM Weber - The Journal of Physiology, 2004 - Wiley Online Library
The thermogenic response of humans depends critically on the coordination of muscle fibre
recruitment and oxidative fuel metabolism. The primary goal of this study was to determine …