Prostate cancer belongs in the class of hormone-dependent cancers, representing a major
cause of cancer incidence in men worldwide. Since upon disease onset almost all prostate …

Despite recent efforts, prostate cancer (PCa) remains one of the most common cancers in
men. Currently, there is no effective treatment for castration-resistant prostate cancer …

Simple Summary Prostate cancer is the most commonly diagnosed cancer in men in the UK,
accounting for the deaths of over 11,000 men per year. A major problem in this disease are …

The Hippo pathway regulates and contributes to several hallmarks of prostate cancer (PCa).
Although the elucidation of YAP function in PCa is in its infancy, emerging studies have shed …

Aberrant up-regulation of Wnt/β-catenin signaling is associated with the development and
progression of prostate cancer, but the underlying mechanism is unclear. Here we show that …

Clinical intervention for patients with advanced prostate cancer (PCa) remains challenging
due to the inevitable recurrence of castration-resistant prostate cancer (CRPC) after …

Although cell polarity plays an important role in epithelial tumorigenesis, the consequence of
polarity protein loss in prostatic tumorigenesis and the underlying mechanisms remain …

Simple Summary The reason for the frequent presence of the TMPRSS2: ERG (T2E) gene
fusion in prostate cancer (PCa) is not fully understood. We were interested in investigating …

The key to preventing mCRPC progression is understanding how androgen-dependent PCa
cells progress to independence and modify their transcriptional repertoire accordingly. We …

Prostate cancer (PC) remains a worldwide challenge, as does the question of how to
distinguish its indolent from its aggressive form to reconcile proper management of the …