Mitochondrial dysfunction has been regarded as a hallmark of diabetic cardiomyopathy. In
addition to their canonical metabolic actions, mitochondria influence various other aspects of …

In diabetic cardiomyopathy (DCM), a major diabetic complication, the myocardium is
structurally and functionally altered without evidence of coronary artery disease …

Diabetic cardiomyopathy is a chronic cardiovascular complication caused by diabetes that is
characterized by changes in myocardial structure and function, ultimately leading to heart …

Ischemic cardiomyopathy (ICM) is a special type of coronary heart disease or an advanced
stage of the disease, which is related to the pathological mechanism of primary dilated …

Mitochondria play an important role in maintaining cardiac homeostasis by supplying the
major energy required for cardiac excitation–contraction coupling as well as controlling the …

Significance: Cardiac function is energetically demanding, reliant on efficient well-coupled
mitochondria to generate adenosine triphosphate and fulfill the cardiac demand. Predictably …

Cardiovascular disease is common in patients with diabetes and is a significant contributor
to the high mortality rates associated with diabetes. Heart failure is common in diabetic …

Mitochondrial homeostasis is critical for keeping functional heart in response to metabolic or
environmental stresses. Mitochondrial fission and fusion (mitochondrial dynamics) play …

Mitochondrial medicine is increasingly discussed as a promising therapeutic approach,
given that mitochondrial defects are thought to contribute to many prevalent diseases and …

Mitochondria are critical for cardiomyocyte survival and maintenance of normal cardiac
function. However, changes in the extra-or intracellular environments during stress can …