The recent boom in microfluidics and combinatorial indexing strategies, combined with low
sequencing costs, has empowered single-cell sequencing technology. Thousands—or even …

Recent advances in single-cell sequencing hold great potential for exploring biological
systems with unprecedented resolution. Sequencing the genome of individual cells can …

Over the past decade, genomic analyses of single cells—the fundamental units of life—have
become possible. Single-cell DNA sequencing has shed light on biological questions that …

Intensively developed in the last few years, single-cell sequencing technologies now
present numerous advantages over traditional sequencing methods for solving the problems …

Advances in genomic technology have enabled the faithful detection and measurement of
mutations and the gene expression profile of cancer cells at the single-cell level. Recently …

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The unabated progress in next-generation sequencing technologies is fostering a wave of
new genomics, epigenomics, transcriptomics and proteomics technologies. These …

Single-cell sequencing technologies can be used to detect the genome, transcriptome and
other multi-omics of single cells. They can show the differences and evolutionary …

The inherent heterogeneity of individual cells in cell populations plays significant roles in
disease development and progression, which is critical for disease diagnosis and treatment …

Most genome-wide assays provide averages across large numbers of cells, but recent
technological advances promise to overcome this limitation. Pioneering single-cell assays …