The positive coreceptor function of complement receptor type 2 [CR2 (CD21)] on B cells is
generally accepted, although its role in the enhancement of antibody production had only …

The complement system—particularly component C3—has been demonstrated to be a key
link between innate and adaptive immunity. The trimolecular complex of complement …

Complement receptors (CRs) CD21 and CD35 form a coreceptor with CD19 and CD81 on
murine B cells that when coligated with the B-cell receptor lowers the threshold of activation …

Abstract Complement receptor type 2 (CR2, CD21) is expressed by both human and murine
B cells and has been demonstrated to play a pivotal role in the humoral immune response …

The involvement of complement in the regulation of antibody responses has been known for
long. By now several additional B cell functions–including cytokine production and antigen …

Complement component C3 has established roles in both innate and adaptive immune
responses. C3 cleavage products function in B cell activation through the complement …

In mice CR1 and CR2 are encoded at a single locus and the two alternatively spliced RNA
transcripts of the CD21 gene generate murine CR1 and CR2 (CR1/2). While the function of …

Abstract The complement receptor 3 (CR3; CD11b/CD18) is present exclusively on
leukocytes, particularly on NK cells, monocytes and polymorphonuclear neutrophils …

C3dg is a cleavage product of the C3 component of complement that can facilitate the
coligation of the complement receptor 2 (CR2/CD21) with the BCR via C3dg/Ag complexes …

We found that transgenic (tg) mice stably expressing a bacterial artificial chromosome (BAC)-
derived human complement receptor type 2 (CR2/CD21) gene demonstrate B cell specific …