Aims: To determine the roles of vitamin D receptor (VDR) in ischemia/reperfusion-induced
myocardial injury and to investigate the underlying mechanisms involved. Results: The …

Myocardial infarction is the leading cause of morbidity and mortality worldwide. Although
myocardial reperfusion after ischemia (I/R) is an effective method to save ischemic …

Accumulating evidence suggests that vitamin D deficiency plays a crucial role in heart
failure. However, whether vitamin D signaling itself plays an important role in …

The aim of this study was to investigate the protective effects of vitamin D (VD) against
myocardial ischemia–reperfusion (I/R) injury in hearts. An I/R injury model was induced by …

Our previous studies showed that the effect of resveratrol preventing mitochondrial
permeability transition pore (mPTP) opening in myocardial ischemia/reperfusion injury was …

Autophagy is an important mechanism for cellular homeostasis and survival during
pathologic stress conditions in the liver, such as ischemia-reperfusion injury. In this study …

Aim To examine the protective effect of vitamin B12 against myocardial ischemia/reperfusion
(I/R) injury and elucidate its underlying mechanism of action. Methods Mice were subjected …

Oxidative stress plays an important role in mediating ventricular remodeling and dysfunction
in heart failure (HF), but its mechanism of action has not been fully elucidated. In this study …

How to provide effective prevention and treatment of myocardial ischemia/reperfusion (I/R)
injury and study of the mechanism underlying I/R injury are hotspots of current research …

Scope This study elucidates the effects of long‐term nutritional preconditioning by
resveratrol on ischemia/reperfusion (I/R) injury and its underlying mechanisms. Methods and …