Pyroptosis: a new regulating mechanism in cardiovascular disease

N Ji, Z Qi, Y Wang, X Yang, Z Yan, M Li… - Journal of …, 2021 - Taylor & Francis
Pyroptosis is a kind of pro-inflammatory cell death. Compared with autophagy and
apoptosis, pyroptosis has unique characteristics in morphology and mechanism …

Role of pyroptosis in cardiovascular diseases

C Jia, H Chen, J Zhang, K Zhou, Y Zhuge, C Niu… - International …, 2019 - Elsevier
Pyroptosis is a form of programmed necrosis, and is morphologically and mechanistically
unique form of programmed cell death compared to others, such as apoptosis and …

Pyroptosis: a pro-inflammatory type of cell death in cardiovascular disease

Q Wang, J Wu, Y Zeng, K Chen, C Wang, S Yang… - Clinica chimica acta, 2020 - Elsevier
Pyroptosis is a pro-inflammatory type of regulated cell death (RCD) characterized by
gasdermin D (GSDMD)-mediated membrane pore formation, cell swelling and rapid lysis …

[HTML][HTML] Pyroptosis: role and mechanisms in cardiovascular disease

X Chen, PC Tian, K Wang, M Wang… - Frontiers in cardiovascular …, 2022 - frontiersin.org
Cardiovascular disease (CVD) is a common disease that poses a huge threat to human
health. Irreversible cardiac damage due to cardiomyocyte death and lack of regenerative …

[HTML][HTML] Role of pyroptosis in cardiovascular diseases and its therapeutic implications

C Zeng, R Wang, H Tan - International journal of biological …, 2019 - ncbi.nlm.nih.gov
Pyroptotic cell death or pyroptosis is characterized by caspase-1-dependent formation of
plasma membrane pores, leading to the release of pro-inflammatory cytokines and cell lysis …

Pyroptosis in the initiation and progression of atherosclerosis

Z Qian, Y Zhao, C Wan, Y Deng, Y Zhuang… - Frontiers in …, 2021 - frontiersin.org
Pyroptosis, a newly discovered form of programmed cell death, is characterized by cell
swelling, the protrusion of large bubbles from the plasma membrane and cell lysis. This …

Current knowledge of pyroptosis in heart diseases

Y Gao, H Shi, Z Dong, F Zhang, A Sun, J Ge - Journal of molecular and …, 2022 - Elsevier
Pyroptosis is a form of pro-inflammatory, necrotic cell death mediated by proteins of the
gasdermin family. Various heart diseases, including myocardial ischemia/reperfusion injury …

Role of pyroptosis in atherosclerosis and its therapeutic implications

B He, Q Nie, F Wang, Y Han, B Yang… - Journal of cellular …, 2021 - Wiley Online Library
Atherosclerosis is a significant cardiovascular burden and a leading cause of death
worldwide, recognized as a chronic sterile inflammatory disease. Pyroptosis is a novel …

Research progresses of molecular mechanism of pyroptosis and its related diseases

W Gong, Y Shi, J Ren - Immunobiology, 2020 - Elsevier
Pyroptosis is a newly discovered untypical form of programmed cell death by inflammatory
response, which is dependent on the classic pathway of Caspase-1 and the non-canonical …

Pyroptosis as a double-edged sword: The pathogenic and therapeutic roles in inflammatory diseases and cancers

Z Liu, C Wang, C Lin - Life Sciences, 2023 - Elsevier
Pyroptosis is a programmed cell death mode discovered in recent years. It is caused by
inflammasomes and the perforation of Gasdermin family proteins, and results in the release …