Browning induction or transplantation of brown adipose tissue (BAT) or brown/beige
adipocytes derived from progenitor or induced pluripotent stem cells (iPSCs) can represent …

The understanding of the mechanisms underlying adipocyte differentiation and function has
greatly benefited from the use of immortalized white preadipocyte cell lines. These cultured …

Brown adipocytes (BAs) are a potential cell source for the treatment of metabolic disease,
including type 2 diabetes. In this report, human pluripotent stem cells (hPSCs) are subject to …

White adipocytes are plastic cells able to reversibly transdifferentiate into brown adipocytes
and into epithelial glandular cells under physiologic stimuli in vivo. These plastic properties …

Brown adipocytes (BAs) represent a specialized cell type that is able to uncouple nutrient
catabolism from ATP generation to dissipate energy as heat. In humans, the brown fat tissue …

Brown adipocytes (BAs) play important roles in body temperature regulation, energy
balance, and carbohydrate and lipid metabolism. Activities of BAs are remarkably …

The potential therapeutic applications of targeting brown adipose tissue open new clinical
avenues in fighting against metabolic pathologies. However, due to the limited extension in …

White adipose tissue (WAT) is no longer considered a depot for energy storage in the form of
triglycerides, but is a secretory organ that releases factors, known as adipokines, capable of …

White adipose tissue (WAT) is a central factor in the development of type 2 diabetes, but
there is a paucity of translational models to study mature adipocytes. We describe a method …

De novo beige adipocyte biogenesis involves the proliferation of progenitor cells in white
adipose tissue (WAT); however, what regulates this process remains unclear. Here, we …