The impact of anti-eosinophilic therapy on exercise capacity and inspiratory muscle strength in patients with severe asthma
E Franceschi, N Drick, J Fuge, P Santus… - ERJ Open …, 2023 - Eur Respiratory Soc
Introduction Exercise limitation is frequently described among asthmatic patients and could
be related to different mechanisms of the pulmonary, cardiovascular and muscular systems …
be related to different mechanisms of the pulmonary, cardiovascular and muscular systems …
[HTML][HTML] Omalizumab treatment and exercise capacity in severe asthmatics–results from a pilot study
C Schäper, S Gläser, SB Felix, A Gogolka, B Koch… - Respiratory …, 2011 - Elsevier
BACKGROUND: In patients with moderate to severe allergic asthma, clinical effectiveness of
omalizumab, an approved anti-IgE-reacting substance, is usually assessed by pulmonary …
omalizumab, an approved anti-IgE-reacting substance, is usually assessed by pulmonary …
Change of lung function in severe eosinophilic asthma undergoing treatment with anti-interleukin-5 monoclonal antibody
L Antonicelli, A Gobbi, MB Bilo, MS Garritani… - 2018 - Eur Respiratory Soc
Background: Steroid-dependent or severe eosinophilic asthma prone to exacerbations
despite maximal ICS/LABA dose are a potential candidate for Mepolizumab. While …
despite maximal ICS/LABA dose are a potential candidate for Mepolizumab. While …
Late Breaking Abstract-Daily physical activity in patients with severe asthma and the effect of anti-IL5 therapy
Background: Daily physical activity (DLA) in patients with severe asthma remains
inadequately explored. The potential effect of biological therapy in DLA in patients with …
inadequately explored. The potential effect of biological therapy in DLA in patients with …
Using the 6-min walk test to assess the clinical response to mepolizumab and conventional therapy in severe eosinophilic asthma
Background Severe asthma limits exercise to avoid respiratory symptoms. The objective of
the present study was to investigate the role of the 6-min walk test (6MWT) in severe asthma …
the present study was to investigate the role of the 6-min walk test (6MWT) in severe asthma …
[HTML][HTML] Mepolizumab improves small airway function in severe eosinophilic asthma
CS Farah, T Badal, N Reed, PG Rogers, GG King… - Respiratory …, 2019 - Elsevier
Background and objective Treatment with mepolizumab in severe eosinophilic asthma
(SEA) significantly reduces exacerbations with modest improvements in symptom control …
(SEA) significantly reduces exacerbations with modest improvements in symptom control …
Predictors of Early and Late Lung Function Improvement in Severe Eosinophilic Asthma on Type2-Biologics in the PRISM Study
DD Pham, JH Lee, HS Kwon, WJ Song, YS Cho, H Kim… - Lung, 2024 - Springer
Background The determinants linked to the short-and long-term improvement in lung
function in patients with severe eosinophilic asthma (SEA) on biological treatment (BioT) …
function in patients with severe eosinophilic asthma (SEA) on biological treatment (BioT) …
[HTML][HTML] Real-life effectiveness of mepolizumab on forced expiratory flow between 25% and 75% of forced vital capacity in patients with severe eosinophilic asthma
A Maglio, C Vitale, S Pellegrino, C Calabrese… - Biomedicines, 2021 - mdpi.com
Severe eosinophilic asthma (SEA) is associated with high peripheral blood and airway
eosinophilia, recurrent disease exacerbations and severe airflow limitation. Eosinophilic …
eosinophilia, recurrent disease exacerbations and severe airflow limitation. Eosinophilic …
Small airways function: evaluation in a population of adult patients with severe asthma and potential use as a response biomarker for anti-IL5 therapy
A Maglio, C Vitale, S Pellegrino, C Calabrese… - 2020 - Eur Respiratory Soc
Background: Asthma is a disease characterized by heterogeneity in clinical presentation
and pathophysiological mechanisms. A novel element of new studies is the role of the …
and pathophysiological mechanisms. A novel element of new studies is the role of the …
Late Breaking Abstract-The impact of treatment with mepolizumab on airway remodeling in patients with severe eosinophilic asthma
M Przybyszowski, I Gross-Sondej, J Zarychta… - 2021 - Eur Respiratory Soc
Background: Severe eosinophilic asthma involves chronic inflammatory process in the
airways leading to changes in airway structure, known as airway remodeling. IL-5 is a …
airways leading to changes in airway structure, known as airway remodeling. IL-5 is a …