Simple Summary Epigenetics is a somatic, heritable pattern of gene expression or cellular
phenotype mediated by structural changes in chromatin that occur without altering the DNA …

The regulation of gene expression is a dynamic process that is influenced by both internal
and external factors. Alteration in the epigenetic profile is a key mechanism in the regulation …

Although genetics determines endocrine phenotypes, it cannot fully explain the great
variability and reversibility of the system in response to environmental changes. Evidence …

After sequencing the human genome, it has become clear that genetic information alone is
not sufficient to understand phenotypic manifestations. The way the DNA code is translated …

In the intricate coordination of cellular processes, the interplay between metabolism and
epigenetics has emerged as an intriguing frontier, revealing a previously overlooked layer of …

Endocrine-disrupting chemicals (EDCs) are chemicals, either natural or synthetic, that can
interfere with the production, distribution, function, metabolism, or excretion of hormones in …

Epigenetic control of gene expression programs is essential for normal organismal
development and cellular function. Abrogation of epigenetic regulation is seen in many …

With the discovery of epigenetic mechanisms that regulate the development and function of
cells and tissues, the life sciences have entered a novel area of disease-relevant research …

Similar to environmental factors, EDCs (endocrine-disrupting chemicals) can influence gene
expression without modifying the DNA sequence. It is commonly accepted that the …

Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …