Background Iron content is increased in the substantia nigra of persons with Parkinson's
disease and may contribute to the pathophysiology of the disorder. Early research suggests …

Parkinson's disease (PD) is associated with increased iron levels in the substantia nigra
(SNc). This study evaluated whether the iron chelator, deferiprone, is well tolerated, able to …

Background Higher nigral iron has been reported in Parkinson's disease (PD). Objective
The aim is to understand the dynamics of nigral iron accumulation in PD and its association …

Background Growing body of evidence suggests that Parkinson's disease (PD) is associated
with oxidative damage via iron accumulation in the substantia nigra (SN). Low …

Aims: The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a
chelation strategy aimed at reducing oxidative damage associated with regional iron …

While the initial causes of Parkinson's disease (PD) are not clearly defined, iron deposition
has long been implicated in the pathogenesis of PD. The substantia nigra of PD patients …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor deficits
accompanying degeneration of substantia nigra pars compactor (SNc) neurons. Although …

Objective: Evidence suggests that abnormal iron metabolism is associated with Parkinson
disease (PD), with raised iron levels found in pathologically affected areas in PD. It is …

Tissue iron levels in the extrapyramidal system of earlier-and later-onset Parkinson's
disease (PD) subjects were evaluated in vivo using a magnetic resonance imaging (MRI) …

Brain iron levels in patients of Parkinson's disease (PD) are usually measured in
postmortem samples or by MRI imaging including R2* and SWI. In this study we performed a …