Cisplatin (CP) is a powerful anticancer agent used in the treatment of a diverse type of
cancers. Oxidative stress is one of the most important side effects limiting the use of cisplatin …

Nephrotoxicity is an important complication in cancer patients undergoing cisplatin therapy.
Oxidative stress, inflammation and apoptosis/necrosis are the major patho-mechanisms of …

Nephrotoxicity remain a major life-threatening complication in cancer patients on cisplatin
chemotherapy. In this study, we investigated the protective effect and possible cellular …

Context Nutraceuticals possessing antioxidant potential have been used to alleviate side
effects exerted by many chemotherapeutics, including cisplatin. Since Apodytes dimidiata E …

We investigated the effects of methanolic leaves extract of Azadirachta indica (MLEN, 500
mg/kg bwt) on cisplatin‐(CP‐) induced nephrotoxicity and oxidative stress in rats. CP (5 …

Background Cisplatin (CP), an effective anticancer agent, carries the risk of impairing
testicular function leading to infertility. The present study aimed at evaluating the protective …

Cisplatin (CisPT) is a chemotherapeutic drug that outcomes in adverse effects. In this study,
we examined the effect of A. hydaspica ethyl acetate extract (AHE) in an animal model of …

This study aimed to assess the protective effect of hesperidin (HES) and rutin (RUT) against
cisplatin‐induced nephrotoxicity in male rats. Cisplatin (5 mg/kg, intraperitoneal) caused …

This study aimed to investigate the beneficial role of Millettia ferruginea extract (MF) in
preventing cisplatin (Cisp) induced nephrotoxicity in rats. A total of 55 metabolites were …

The present study investigated the modulatory role of phenolic extract of soybean (PESB) in
a rat model of nephrotoxic acute renal failure induced by cisplatin. Cisplatin (2mg/kg/day) …