Methanolic extract of Ephedra alata ameliorates cisplatin-induced nephrotoxicity and hepatotoxicity through reducing oxidative stress and genotoxicity
F Sioud, I Ben Toumia, A Lahmer, R Khlifi… - … Science and Pollution …, 2020 - Springer
Cisplatin (CP) is a powerful anticancer agent used in the treatment of a diverse type of
cancers. Oxidative stress is one of the most important side effects limiting the use of cisplatin …
cancers. Oxidative stress is one of the most important side effects limiting the use of cisplatin …
Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage
Nephrotoxicity is an important complication in cancer patients undergoing cisplatin therapy.
Oxidative stress, inflammation and apoptosis/necrosis are the major patho-mechanisms of …
Oxidative stress, inflammation and apoptosis/necrosis are the major patho-mechanisms of …
The renoprotective activity of hesperetin in cisplatin induced nephrotoxicity in rats: Molecular and biochemical evidence
Nephrotoxicity remain a major life-threatening complication in cancer patients on cisplatin
chemotherapy. In this study, we investigated the protective effect and possible cellular …
chemotherapy. In this study, we investigated the protective effect and possible cellular …
Ameliorative effect of Apodytes dimidiata on cisplatin-induced nephrotoxicity in Wistar rats
MK Divya, L Lincy, AC Raghavamenon… - Pharmaceutical …, 2016 - Taylor & Francis
Context Nutraceuticals possessing antioxidant potential have been used to alleviate side
effects exerted by many chemotherapeutics, including cisplatin. Since Apodytes dimidiata E …
effects exerted by many chemotherapeutics, including cisplatin. Since Apodytes dimidiata E …
Azadirachta indica Attenuates Cisplatin‐Induced Nephrotoxicity and Oxidative Stress
AE Abdel Moneim, MS Othman… - BioMed research …, 2014 - Wiley Online Library
We investigated the effects of methanolic leaves extract of Azadirachta indica (MLEN, 500
mg/kg bwt) on cisplatin‐(CP‐) induced nephrotoxicity and oxidative stress in rats. CP (5 …
mg/kg bwt) on cisplatin‐(CP‐) induced nephrotoxicity and oxidative stress in rats. CP (5 …
[HTML][HTML] Acacia hydaspica ethyl acetate extract protects against cisplatin-induced DNA damage, oxidative stress and testicular injuries in adult male rats
Background Cisplatin (CP), an effective anticancer agent, carries the risk of impairing
testicular function leading to infertility. The present study aimed at evaluating the protective …
testicular function leading to infertility. The present study aimed at evaluating the protective …
[HTML][HTML] Acacia hydaspica R. Parker ethyl-acetate extract abrogates cisplatin-induced nephrotoxicity by targeting ROS and inflammatory cytokines
Cisplatin (CisPT) is a chemotherapeutic drug that outcomes in adverse effects. In this study,
we examined the effect of A. hydaspica ethyl acetate extract (AHE) in an animal model of …
we examined the effect of A. hydaspica ethyl acetate extract (AHE) in an animal model of …
Hesperidin and rutin, antioxidant citrus flavonoids, attenuate cisplatin‐induced nephrotoxicity in rats
KM Kamel, OM Abd El‐Raouf… - … of Biochemical and …, 2014 - Wiley Online Library
This study aimed to assess the protective effect of hesperidin (HES) and rutin (RUT) against
cisplatin‐induced nephrotoxicity in male rats. Cisplatin (5 mg/kg, intraperitoneal) caused …
cisplatin‐induced nephrotoxicity in male rats. Cisplatin (5 mg/kg, intraperitoneal) caused …
[HTML][HTML] Millettia ferruginea extract attenuates cisplatin-induced alterations in kidney functioning, DNA damage, oxidative stress, and renal tissue morphology
M Yassir, M Tir, A Mufti, A Feriani, B Faidi, N Tlili… - Arabian Journal of …, 2022 - Elsevier
This study aimed to investigate the beneficial role of Millettia ferruginea extract (MF) in
preventing cisplatin (Cisp) induced nephrotoxicity in rats. A total of 55 metabolites were …
preventing cisplatin (Cisp) induced nephrotoxicity in rats. A total of 55 metabolites were …
Phenolic extract of soybean (Glycine max) attenuates cisplatin-induced nephrotoxicity in rats
M Ekor, GO Emerole, EO Farombi - Food and Chemical Toxicology, 2010 - Elsevier
The present study investigated the modulatory role of phenolic extract of soybean (PESB) in
a rat model of nephrotoxic acute renal failure induced by cisplatin. Cisplatin (2mg/kg/day) …
a rat model of nephrotoxic acute renal failure induced by cisplatin. Cisplatin (2mg/kg/day) …
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