A potential therapeutic target in traditional Chinese medicine for ulcerative colitis: Macrophage polarization

Z Yang, S Lin, W Feng, Y Liu, Z Song, G Pan… - Frontiers in …, 2022 - frontiersin.org
Intestinal macrophages are the main participants of intestinal immune homeostasis and
intestinal inflammation. Under different environmental stimuli, intestinal macrophages can …

A potential therapeutic approach for ulcerative colitis: targeted regulation of macrophage polarization through phytochemicals

K Wang, T Mao, X Lu, M Wang, Y Yun, Z Jia… - Frontiers in …, 2023 - frontiersin.org
Ulcerative colitis (UC), a type of inflammatory bowel disease characterized by recurring and
incurable symptoms, causes immense suffering and economic burden for patients due to the …

Macrophage polarization in inflammatory bowel disease

K Zhang, J Guo, W Yan, L Xu - Cell Communication and Signaling, 2023 - Springer
The growing prevalence of inflammatory bowel disease (IBD) has encouraged research
efforts, which have contributed to gradual improvements in our understanding of IBD …

Macrophage-based nanotherapeutic strategies in ulcerative colitis

J Zhang, Y Zhao, T Hou, H Zeng, D Kalambhe… - Journal of Controlled …, 2020 - Elsevier
Macrophages, an important component of the innate immune response, are a key regulator
of intestinal microenvironment homeostasis. These cells essentially contribute to chronic …

Macrophage polarization: an effective approach to targeted therapy of inflammatory bowel disease

Y Du, L Rong, Y Cong, L Shen, N Zhang… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Inflammatory bowel disease (IBD) is a systemic disease with immune
abnormalities that can affect the entire digestive tract. A high percentage of patients with IBD …

Potential activity of traditional Chinese medicine against ulcerative colitis: a review

Y Liu, BG Li, YH Su, RX Zhao, P Song, H Li… - Journal of …, 2022 - Elsevier
Ethnic pharmacological relevance Plant materials are used as complementary and
alternative therapies all over the world for the treatment of various diseases. Ulcerative …

Traditional Chinese Medicine: A promising strategy to regulate the imbalance of bacterial flora, impaired intestinal barrier and immune function attributed to ulcerative …

M Wang, R Fu, D Xu, Y Chen, S Yue, S Zhang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Globally, plant materials are widely used as an additional
and alternative therapy for the treating of diverse diseases. Ulcerative colitis (UC) is a …

Loganin inhibits macrophage M1 polarization and modulates sirt1/NF-κB signaling pathway to attenuate ulcerative colitis

S Liu, H Shen, J Li, Y Gong, H Bao, J Zhang, L Hu… - …, 2020 - Taylor & Francis
Loganin, a major bioactive iridoid glycoside derived from Cornus officinalis, exerts different
beneficial biological properties. Recently, loganin has been reported to exhibit potential anti …

Traditional Chinese medicine in regulating macrophage polarization in immune response of inflammatory diseases

S Chen, J Zeng, R Li, Y Zhang, Y Tao, Y Hou… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Numerous studies have demonstrated that various
traditional Chinese medicines (TCMs) exhibit potent anti-inflammatory effects against …

Qingre Xingyu recipe exerts inhibiting effects on ulcerative colitis development by inhibiting TNFα/NLRP3/Caspase-1/IL-1β pathway and macrophage M1 polarization

L Ning, N Ye, B Ye, Z Miao, T Cao, W Lu, D Xu… - Cell Death …, 2023 - nature.com
As a chronic inflammatory bowel disease, ulcerative colitis (UC) imposes a significant
burden on public healthcare worldwide due to its increasing morbidity. Chinese medicines …