Intervertebral disc degeneration (IVDD) has been the major contributor to chronic lower back
pain (LBP). Abnormal apoptosis, senescence, and pyroptosis of IVD cells, extracellular …

Many of the causes of low back pain are still unknown; sufficient evidence indicates that both
degenerative and mechanical change within the intervertebral disk (IVD) is a relevant factor …

Low back pain (LBP) is a common musculoskeletal symptom, which can be developed in
multiple clinical diseases. It is widely recognized that intervertebral disc (IVD) degeneration …

Intervertebral disc (IVD) degeneration is a major contributing factor for discogenic low back
pain (LBP), causing a significant global disability. The IVD consists of an inner core …

Degeneration of the intervertebral discs (IVDs) is a major contributor to back, neck and
radicular pain. IVD degeneration is characterized by increases in levels of the …

Intervertebral disc degeneration (IVD) can result in chronic low back pain, a common cause
of morbidity and disability. Inflammation has been associated with IVD degeneration …

Intervertebral disc (IVD) degeneration (IDD) is one of the major causes of back pain, a
condition that represents a serious socio-economic burden. Deeper knowledge of the …

Background Intervertebral disc degeneration (IDD) is a leading cause of low back pain
(LBP), posing a significant socioeconomic burden. Recent studies highlight the crucial role …

Degeneration of the intervertebral disc is clinically considered to be an important source of
pain in patients with low-back pain. Disc deterioration and/or degeneration may influence …

Background Chronic low back pain (LBP) is the most common cause of disability worldwide.
New ideas surrounding LBP are emerging that are based on interactions between …