Hereditary hemochromatosis is the result of pathogenic variants in multiple genes that can
result in increased body iron stores with excess iron deposited in various organs, including …

The discovery of hepcidin in 2000 and the subsequent unprecedented explosion of research
and discoveries in the iron field have dramatically changed our understanding of human …

Hereditary hemochromatosis (HH) comprises a group of inherited disorders of iron
metabolism that can result in progressive iron overload, morbidity, and mortality, generally in …

Hemochromatosis (HC) is a genetically heterogeneous disorder in which uncontrolled
intestinal iron absorption may lead to progressive iron overload (IO) responsible for …

Haemochromatosis is a genetic disease caused by hepcidin deficiency, responsible for an
increase in intestinal iron absorption. Haemochromatosis is associated with homozygosity …

Iron overload disorders represent an important class of human diseases. Of the primary iron
overload conditions, by far the most common and best studied is HFE-related …

Hereditary hemochromatosis (HH) refers to several inherited disorders of iron metabolism
leading to tissue iron overload. Classical HH is associated with mutations in HFE (C282Y …

This review acknowledges the recent and dramatic advancement in the field of
hemochromatosis and highlights the surprising analogies with a prototypic endocrine …

Hereditary hemochromatosis (HH) encompasses several inherited disorders of iron
homeostasis characterized by increased gastrointestinal iron absorption and tissue iron …

In the late 1800s, hemochromatosis was considered an odd autoptic finding. More than a
century later, it was finally recognized as a hereditary, multi-organ disorder associated with a …