The objective of the current study was to characterize the effects of DE-71 (a commercial
polybrominated diphenyl ether mixture containing mostly tetra-and penta-bromodiphenyl …

Previous studies demonstrated that perinatal exposure to polybrominated diphenyl ethers
(PBDEs), a major class of brominated flame retardants, may affect thyroid hormone (TH) …

Developmental effects of polybrominated diphenyl ethers (PBDEs) have been suspected
due to their structural similarities to polychlorinated biphenyls (PCBs). This study evaluated …

Thyroid hormone concentrations, hepatic enzyme activities and tissue concentrations of 2,
2′, 4, 4′, 5-pentabromodiphenyl ether (PBDE-99) were evaluated in Wistar rats (dams …

Decabrominated diphenyl ether (PBDE 209) is the second most used brominated flame
retardant (BFRs). Many studies have shown that some of the BFRs act as endocrine …

Polybrominated diphenyl ethers (PBDEs), used as flame retardants, are ubiquitous
environmental contaminants. PBDEs act as endocrine disruptors via alterations in thyroid …

Background Polybrominated diphenyl ethers (PBDEs) are capable of disrupting thyroid
hormone homeostasis. PBDE-47 (2, 2′, 4, 4′-tetrabromodiphenyl ether) is one of the most …

In experimental animals fed standard laboratory diets, penta-BDE mixtures can decrease
circulating thyroid hormone and liver vitamin A concentrations. A substantial number of …

Abstract DE-71, a commercial mixture, was used to test the sensitivity of the female and male
pubertal protocol to detect thyroid active chemicals. These protocols are being evaluated for …

Polybrominated diphenyl ethers (PBDEs) are a class of polyhalogenated aromatic
compounds commercially used as fire retardants in consumer products. These compounds …