Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by interstitial remodelling,
leading to compromised lung function. Cellular senescence markers are detectable within …

Fibrosing interstitial lung diseases (ILDs) are chronic and ultimately fatal age-related lung
diseases characterized by the progressive and irreversible accumulation of scar tissue in the …

Cellular senescence (CS) is increasingly implicated in the etiology of age-related diseases.
While CS can facilitate physiological processes such as tissue repair and wound healing …

Idiopathic pulmonary fibrosis (IPF) is a progressive fatal lung disorder with an unknown
etiology and very limited therapeutic options. The incidence and severity of IPF increase with …

Pulmonary fibrosis is a chronic and fatal lung disease that significantly impacts the aging
population globally. To date, anti-fibrotic, immunosuppressive, and other adjunct therapy …

Background Cellular senescence is a key mechanism that drives age-related diseases, but
has yet to be targeted therapeutically in humans. Idiopathic pulmonary fibrosis (IPF) is a …

Idiopathic pulmonary fibrosis (IPF) is a fatal chronic lung disease characterized by
progressive scarring of the lung tissue, leading to respiratory failure. There is no cure for IPF …

Aging is an inevitable and complex natural phenomenon due to the increase in age. Cellular
senescence means a non-proliferative but viable cellular physiological state. It is the basis of …

Cellular senescence is a cell fate decision and stress response that entails a permanent
arrest of cell proliferation coupled to a complex secretory phenotype. Senescent cells …

Cellular senescence represents a state of irreversible cell cycle arrest occurring naturally or
in response to exogenous stressors. Following the initial arrest, progressive phenotypic …