Evolution of increased susceptibility to infectious diseases in age structured populations

S Lundberg - Journal of theoretical biology, 1990 - Elsevier
Current theory on the epidemiology of infectious diseases in genetically heterogeneous host
populations ignores age structure. Thus, the possibility that microparasites might have …

Within-host evolution and virulence in microparasites

JB André, B Godelle - Journal of theoretical biology, 2006 - Elsevier
An important aspect of microparasite biology is the fact that infections are populations of
thousands of microbes. As any population, infections are hence subject to two main types of …

[PDF][PDF] Can infectious diseases eradicate host species? The effect of infection-age structure

J Ponce, HR Thieme - Mathematical Biosciences and Engineering, 2023 - aimspress.com
It is a fundamental question in mathematical epidemiology whether deadly infectious
diseases only lead to a mere decline of their host populations or whether they can cause …

Subthreshold and superthreshold coexistence of pathogen variants: the impact of host age-structure

M Martcheva, SS Pilyugin, RD Holt - Mathematical biosciences, 2007 - Elsevier
It is well known that in the most general epidemic models with multiple pathogen variants a
competitive exclusion principle is valid, such that the variant with the highest reproduction …

Geriatric infections: Decreased immunity or evolved opportunists?

U Baig, V Laxmi, A Ojha, M Watve - Journal of biosciences, 2020 - Springer
In host–parasite co-evolution, parasites are assumed to have an advantage owing to their
shorter generation time. Evolution of pathogens within the lifetime of a host individual is …

Populations and infectious diseases: dynamics and evolution

M Kakehashi - Researches on Population Ecology, 1996 - Springer
The host-parasite or host-pathogen system was analyzed from dynamical and evolutionary
viewpoints using simple mathematical models incorporating vertical transmission, immunity …

Incorporating immunological ideas in epidemiological models

J Dushoff - Journal of theoretical biology, 1996 - Elsevier
Many diseases show important interactions between epidemiology and immunology. Both
models and datat suggest that epidemiologically controlled variables, like frequency and …

The evolution of pathogen virulence: Effects of transitions between host types

PD Williams, SJ Kamel - Journal of theoretical biology, 2018 - Elsevier
Much of evolutionary epidemiology theory is derived from a perspective in which all hosts,
and all parasites, are epidemiologically equivalent. This stands in contrast to the well …

Human disease and the evolution of pathogen virulence

RB Johnson - Journal of theoretical biology, 1986 - Elsevier
Theorists who make a priori generalizations about the tendency of host-parasite systems to
co-evolve toward commensalism or increased parasitism err because they do not consider …

DYNAMICAL MODELS OF EPIDEMICS IN AGE-STRUCTURED POPULATIONS--ANALYSIS AND SIMPLIFICATION.

VA Andreasen - 1988 - elibrary.ru
Long term persistence of infectious diseases depends on the infection and recovery
processes within individual hosts, as well as on the vital dynamics of the host population and …