Increased levels of circulating interleukin 6, interleukin 8, C-reactive protein, and risk of lung cancer

SR Pine, LE Mechanic, L Enewold… - Journal of the …, 2011 - academic.oup.com
Background Previous studies that were based primarily on small numbers of patients
suggested that certain circulating proinflammatory cytokines may be associated with lung …

Serum concentrations of cytokines and lung cancer survival in African Americans and Caucasians

L Enewold, LE Mechanic, ED Bowman, YL Zheng… - … Biomarkers & Prevention, 2009 - AACR
Accumulating evidence suggests a role for inflammation in the development and
progression of cancer. Our group recently identified a cytokine gene signature in lung tissue …

Circulating inflammation markers and prospective risk for lung cancer

MS Shiels, RM Pfeiffer, A Hildesheim… - Journal of the …, 2013 - academic.oup.com
Background Despite growing recognition of an etiologic role for inflammation in lung
carcinogenesis, few prospective epidemiologic studies have comprehensively investigated …

Circulating levels of inflammatory markers and cancer risk in the health aging and body composition cohort

D Il'yasova, LH Colbert, TB Harris, AB Newman… - … Biomarkers & Prevention, 2005 - AACR
Background: Chronic inflammation is associated with processes that contribute to the onset
or progression of cancer. This study examined the relationships between circulating levels of …

Systematic review of the association between circulating interleukin-6 (IL-6) and cancer

K Heikkilä, S Ebrahim, DA Lawlor - European journal of cancer, 2008 - Elsevier
Our aim was to systematically review the epidemiologic evidence for an association of
circulating interleukin-6 (IL-6), an inflammatory cytokine and cancer. We systematically …

Circulating interleukin‐6 level is a prognostic marker for survival in advanced nonsmall cell lung cancer patients treated with chemotherapy

CH Chang, CF Hsiao, YM Yeh… - … journal of cancer, 2013 - Wiley Online Library
Lung cancer is the leading cause of cancer death worldwide as well as in Taiwan.
Interleukin‐6 (IL‐6) is a multifunctional cytokine and has been implicated in tumor …

Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis

K Heikkilä, R Harris, G Lowe, A Rumley, J Yarnell… - Cancer causes & …, 2009 - Springer
Objective We investigated the associations of circulating C-reactive protein (CRP) and
interleukin-6 (IL-6) with cancer risk. Methods We examined the associations of CRP and IL-6 …

Elevated serum levels of interleukin-8 in advanced non-small cell lung cancer patients: relationship with prognosis

M Orditura, F De Vita, G Catalano… - Journal of interferon & …, 2002 - liebertpub.com
Interleukin-8 (IL-8) is a pleiotropic cytokine that has also been shown to exert effects relevant
to cancer growth and progression. Cancer progression is believed to be contributed to by …

Serum interleukin‐6 associated with hepatocellular carcinoma risk: A nested case–control study

W Ohishi, JB Cologne, S Fujiwara… - … journal of cancer, 2014 - Wiley Online Library
Inflammatory markers have been associated with increased risk of several cancers,
including colon, lung, breast and liver, but the evidence is inconsistent. We conducted a …

[HTML][HTML] High systemic IL-6 is associated with worse prognosis in patients with non-small cell lung cancer

EM Silva, VS Mariano, PRA Pastrez, MC Pinto… - PloS one, 2017 - journals.plos.org
Characteristic cytokine patterns have been described in different cancer patients and they
are related to their diagnosis, prognosis, prediction of treatment responses and survival. A …