Tumor cell lines are often used as models for the study of nanoparticle− cell interactions.
Here we demonstrate that carboxy (PS-COOH) and amino functionalized (PS-NH2) …

The mechanism (s) of nanoparticle–cell interactions are still not understood. At present there
is little knowledge of the relevant length‐and timescales for nanoparticle intracellular entry …

Nanoparticles may address challenges by human diseases through improving diagnosis,
vaccination and treatment. The uptake mechanism regulates the type of threat a particle …

Abstract Background Nanoparticles (NPs) are currently used in a wide variety of fields such
as technology, medicine and industry. Due to the novelty of these applications and to ensure …

Nanoparticles and their interaction with human cells have been a focus of many groups
during the past decade. We discuss and review here the progress in the field of …

Nanoparticle uptake by cells has been studied for applications both in nanomedicine and in
nanosafety. While the majority of studies have focused on the biological mechanisms …

Nanoparticle (NPs) delivery systems in vivo promises to overcome many obstacles
associated with the administration of drugs, vaccines, plasmid DNA and RNA materials …

Delivery and toxicity are critical issues facing nanomedicine research. Currently, there is
limited understanding and connection between the physicochemical properties of a …

Neutrophils are the most abundant circulating leukocyte and the first point of contact
between many drug delivery formulations and human cells. Despite their prevalence and …

Nanoparticle uptake by living cells is governed by chemical interactions between functional
groups on the nanoparticle as well as the receptors on cell surfaces. Here we have …