Trends in the design and use of elastin-like recombinamers as biomaterials

A Ibáñez-Fonseca, T Flora, S Acosta… - Matrix Biology, 2019 - Elsevier
Abstract Elastin-like recombinamers (ELRs), which derive from one of the repetitive domains
found in natural elastin, have been intensively studied in the last few years from several …

Recent contributions of elastin-like recombinamers to biomedicine and nanotechnology

F Javier Arias, M Santos… - Current topics in …, 2014 - ingentaconnect.com
The emergence of the new scientific field known as nanomedicine is being catalyzed by
multiple improvements in nanoscience techniques and significant progress in materials …

Elastin‐like recombinamers: Biosynthetic strategies and biotechnological applications

A Girotti, A Fernández‐Colino, IM López… - Biotechnology …, 2011 - Wiley Online Library
The past few decades have witnessed the development of novel naturally inspired
biomimetic materials, such as polysaccharides and proteins. Likewise, the seemingly …

Emerging applications of multifunctional elastin-like recombinamers

JC Rodríguez-Cabello, L Martín, A Girotti… - …, 2011 - Taylor & Francis
Elastin-like recombinamers have grown in popularity in the field of protein-inspired
biomimetic materials and have found widespread use in biomedical applications. Modern …

Elastin-like polypeptides in drug delivery

JC Rodríguez-Cabello, FJ Arias, MA Rodrigo… - Advanced drug delivery …, 2016 - Elsevier
The use of recombinant elastin-like materials, or elastin-like recombinamers (ELRs), in drug-
delivery applications is reviewed in this work. Although ELRs were initially used in similar …

Biocompatibility of two model elastin‐like recombinamer‐based hydrogels formed through physical or chemical cross‐linking for various applications in tissue …

A Ibáñez‐Fonseca, TL Ramos… - Journal of tissue …, 2018 - Wiley Online Library
Biocompatibility studies, especially innate immunity induction, in vitro and in vivo cytotoxicity,
and fibrosis, are often lacking for many novel biomaterials including recombinant protein …

[HTML][HTML] Self-assembly in elastin-like recombinamers: a mechanism to mimic natural complexity

L Quintanilla-Sierra, C García-Arévalo… - Materials Today Bio, 2019 - Elsevier
The topic of self-assembled structures based on elastin-like recombinamers (ELRs, ie,
elastin-like polymers recombinantly bio-produced) has released a noticeable amount of …

Elastin‐like recombinamers: deconstructing and recapitulating the functionality of Extracellular Matrix proteins using recombinant protein polymers

S Acosta, L Quintanilla‐Sierra, L Mbundi… - Advanced Functional …, 2020 - Wiley Online Library
In the development of tissue engineering strategies to replace, remodel, regenerate, or
support damaged tissue, the development of bioinspired biomaterials that recapitulate the …

Development and characterisation of novel cross-linked bio-elastomeric materials

EM Srokowski, KA Woodhouse - Journal of biomaterials science …, 2008 - Taylor & Francis
Recombinantly-engineered elastin-like polypeptides (ELPs) possess many of the favourable
attributes of the native elastin protein, making them an attractive option for designing …

Synthesis of genetically engineered protein polymers (recombinamers) as an example of advanced self-assembled smart materials

JC Rodríguez-Cabello, A Girotti, A Ribeiro… - … in regenerative medicine …, 2012 - Springer
In this chapter, we describe two methods for bio-producing recombinant repetitive
polypeptide polymers for use in biomedical devices. These polymers, known as elastin-like …