Marfan syndrome (MFS) is a connective tissue disorder that is often associated with 25
fibrillin-1 (Fbn1) gene mutation and characterized by cardiovascular alterations, 26 …

Marfan syndrome (MFS) is a connective tissue disorder that is often associated with the
fibrillin-1 (Fbn1) gene mutation and characterized by cardiovascular alterations …

Marfan syndrome (MFS), resulting from mutations in the fibrillin 1 gene (Fbn1), not only
causes life-threatening aortic complications but also affects multiple organ systems. We …

Marfan Syndrome (MFS) is a connective tissue disorder due to mutations in fibrillin-1 (Fbn1),
where a Fbn1 missense mutation (Fbn1C1039G/+) can result in systemic increases in the …

Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1
gene, which encodes fibrillin-1, a protein essential for the formation and stabilization of …

Abstract In individuals with Marfan Syndrome (MFS), fibrillin-1 gene (FBN1) mutations can
lead to vascular wall weakening and dysfunction. The experimental mouse model of MFS …

Marfan syndrome (MFS) is a connective tissue disorder (CTD) associated with mutations in
fibrillin-1 (Fbn1), leading to chronic systemic increases in transforming growth factor-β (TGF …

Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the fibrillin‐1
(FBN1) gene. This mutation manifests in a variety of phenotypic changes with a notable …

Background: Aging-associated vascular and cerebrovascular dysfunction is prevalent in
many connective tissue disorders. Marfan syndrome (MFS) is the most common …

2 Circ Genom Precis Med. 2018; 11: e002185. DOI: 10.1161/CIRCGEN. 118.002185 June
2018 different variants, however, is that the precise mechanism of organ damage in MFS is …