[HTML][HTML] Clinical and prognostic significance of e1a2 BCR-ABL1 transcript subtype in chronic myeloid leukemia
Chronic myeloid leukemia (CML) is characterized by the presence of BCR-ABL1 fusion
gene. In over 95% of CML patients, the typical BCR-ABL1 transcript subtypes are e13a2 …
gene. In over 95% of CML patients, the typical BCR-ABL1 transcript subtypes are e13a2 …
Is the BCR-ABL1 transcript type in chronic myeloid leukaemia relevant?
SE Langabeer - Medical Oncology, 2013 - Springer
In a recent edition of Medical Oncology, Bennour et al.[1] describe differences between the
two most common BCRABL1 transcript types in a cohort of patients with chronic myeloid …
two most common BCRABL1 transcript types in a cohort of patients with chronic myeloid …
Impact of BCR-ABL transcript type on outcome in patients with chronic-phase CML treated with tyrosine kinase inhibitors
P Jain, H Kantarjian, KP Patel… - Blood, The Journal …, 2016 - ashpublications.org
The most common breakpoint cluster region gene-Abelson murine leukemia viral oncogene
homolog 1 (BCR-ABL) transcripts in chronic myeloid leukemia (CML) are e13a2 (b2a2) and …
homolog 1 (BCR-ABL) transcripts in chronic myeloid leukemia (CML) are e13a2 (b2a2) and …
Clinical characteristics and prognostic significance of chronic myeloid leukemia with rare BCR-ABL1 transcripts
M Xue, Q Wang, L Huo, L Wen, X Yang… - Leukemia & …, 2019 - Taylor & Francis
The prognostic significance of rare BCR-ABL1 transcripts is uncertain in the tyrosine kinase
inhibitor (TKI) era. In this retrospective study, 40 (1.7%) patients with rare BCR-ABL1 …
inhibitor (TKI) era. In this retrospective study, 40 (1.7%) patients with rare BCR-ABL1 …
Chronic Myeloid Leukemia with e19a2 BCR-ABL1 Transcripts and Marked Thrombocytosis: The Role of Molecular Monitoring
SE Langabeer, SL McCarron, J Kelly… - Case reports in …, 2012 - Wiley Online Library
While most patients with chronic myeloid leukemia (CML) express either e13a2 or e14a2
BCR-ABL1 transcripts, a significant minority expresses variant transcripts, of which e19a2 is …
BCR-ABL1 transcripts, a significant minority expresses variant transcripts, of which e19a2 is …
[HTML][HTML] Prognostic significance of transcript-type BCR-ABL1 in chronic myeloid leukemia
Chronic myeloid leukemia (CML) is characterized by the presence of the BCR-ABL1 fusion
gene. In more than 95% of CML patients, the typical BCR-ABL1 transcript subtypes are …
gene. In more than 95% of CML patients, the typical BCR-ABL1 transcript subtypes are …
[HTML][HTML] Response to Imatinib therapy is inferior for e13a2 BCR-ABL1 transcript type in comparison to e14a2 transcript type in chronic myeloid leukaemia
G Greenfield, R McMullan, N Robson, J McGimpsey… - BMC hematology, 2019 - Springer
Abstract Background The BCR-ABL1 fusion gene underlying the pathogenesis of CML can
arise from a variety of breakpoints. The e13a2 and e14a2 transcripts formed by breakpoints …
arise from a variety of breakpoints. The e13a2 and e14a2 transcripts formed by breakpoints …
Chronic myeloid leukemia (CML) with P190BCR-ABL: analysis of characteristics, outcomes, and prognostic significance
D Verma, HM Kantarjian, D Jones… - Blood, The Journal …, 2009 - ashpublications.org
The most common BCR-ABL transcripts in chronic myeloid leukemia (CML) are e13a2
(b2a2) and e14a2 (b3a2). Other transcripts such as e1a2 are rare and their outcome with …
(b2a2) and e14a2 (b3a2). Other transcripts such as e1a2 are rare and their outcome with …
Chronic myeloid leukemia with e14a3 BCR-ABL transcript: Analysis of characteristics and prognostic significance
G Xiaomin, Z Yong, P Jinlan, Q Huiying… - Leukemia & …, 2015 - Taylor & Francis
Chronic myeloid leukemia (CML) is characterized by Philadelphia chromosome (Ph) and
BCR-ABL fusion genes. This study retrospectively analyzed 2381 CML patients with Ph …
BCR-ABL fusion genes. This study retrospectively analyzed 2381 CML patients with Ph …
The impact of BCR‐ABL1 transcript type on tyrosine kinase inhibitor responses and outcomes in patients with chronic myeloid leukemia
A Ercaliskan, AE Eskazan - Cancer, 2018 - Wiley Online Library
Although the majority of patients with chronic myeloid leukemia do well with treatment with
tyrosine kinase inhibitors (TKIs), some patients still have inferior outcomes. There are many …
tyrosine kinase inhibitors (TKIs), some patients still have inferior outcomes. There are many …
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