Chronic myeloid leukemia (CML) is characterized by the presence of BCR-ABL1 fusion
gene. In over 95% of CML patients, the typical BCR-ABL1 transcript subtypes are e13a2 …

In a recent edition of Medical Oncology, Bennour et al.[1] describe differences between the
two most common BCRABL1 transcript types in a cohort of patients with chronic myeloid …

The most common breakpoint cluster region gene-Abelson murine leukemia viral oncogene
homolog 1 (BCR-ABL) transcripts in chronic myeloid leukemia (CML) are e13a2 (b2a2) and …

The prognostic significance of rare BCR-ABL1 transcripts is uncertain in the tyrosine kinase
inhibitor (TKI) era. In this retrospective study, 40 (1.7%) patients with rare BCR-ABL1 …

While most patients with chronic myeloid leukemia (CML) express either e13a2 or e14a2
BCR-ABL1 transcripts, a significant minority expresses variant transcripts, of which e19a2 is …

Chronic myeloid leukemia (CML) is characterized by the presence of the BCR-ABL1 fusion
gene. In more than 95% of CML patients, the typical BCR-ABL1 transcript subtypes are …

Abstract Background The BCR-ABL1 fusion gene underlying the pathogenesis of CML can
arise from a variety of breakpoints. The e13a2 and e14a2 transcripts formed by breakpoints …

The most common BCR-ABL transcripts in chronic myeloid leukemia (CML) are e13a2
(b2a2) and e14a2 (b3a2). Other transcripts such as e1a2 are rare and their outcome with …

Chronic myeloid leukemia (CML) is characterized by Philadelphia chromosome (Ph) and
BCR-ABL fusion genes. This study retrospectively analyzed 2381 CML patients with Ph …

Although the majority of patients with chronic myeloid leukemia do well with treatment with
tyrosine kinase inhibitors (TKIs), some patients still have inferior outcomes. There are many …