Global and targeted serum metabolic profiling of colorectal cancer progression
Y Long, B Sanchez‐Espiridion, M Lin, L White… - Cancer, 2017 - Wiley Online Library
BACKGROUND Patients with colorectal adenoma polyps (PLPs) are at higher risk for
developing colorectal cancer (CRC). However, the development of improved and robust …
developing colorectal cancer (CRC). However, the development of improved and robust …
[HTML][HTML] Changing metabolic patterns along the colorectal adenoma–carcinoma sequence
J Tevini, SK Eder, U Huber-Schönauer… - Journal of clinical …, 2022 - mdpi.com
Colorectal cancer (CRC) is a major public health burden and one of the leading causes of
cancer-related deaths worldwide. Screening programs facilitate early diagnosis and can …
cancer-related deaths worldwide. Screening programs facilitate early diagnosis and can …
Metabolomic profiling identified serum metabolite biomarkers and related metabolic pathways of colorectal cancer
C Zhang, S Zhou, H Chang, F Zhuang, Y Shi… - Disease …, 2021 - Wiley Online Library
Background. The screening and early detection of colorectal cancer (CRC) still remain a
challenge due to the lack of reliable and effective serum biomarkers. Thus, this study is …
challenge due to the lack of reliable and effective serum biomarkers. Thus, this study is …
[HTML][HTML] A quantitative multimodal metabolomic assay for colorectal cancer
F Farshidfar, KA Kopciuk, R Hilsden, SE McGregor… - BMC cancer, 2018 - Springer
Background Early diagnosis of colorectal cancer (CRC) simplifies treatment and improves
treatment outcomes. We previously described a diagnostic metabolomic biomarker derived …
treatment outcomes. We previously described a diagnostic metabolomic biomarker derived …
A prospective study of serum metabolites and colorectal cancer risk
BACKGROUND Colorectal cancer is highly prevalent, and the vast majority of cases are
thought to be sporadic, although few risk factors have been identified. Using metabolomics …
thought to be sporadic, although few risk factors have been identified. Using metabolomics …
Colorectal cancer detection using targeted serum metabolic profiling
Colorectal cancer (CRC) is one of the most prevalent and deadly cancers in the world.
Despite an expanding knowledge of its molecular pathogenesis during the past two …
Despite an expanding knowledge of its molecular pathogenesis during the past two …
[HTML][HTML] Untargeted metabolomics reveals major differences in the plasma metabolome between colorectal cancer and colorectal adenomas
T Gumpenberger, S Brezina, P Keski-Rahkonen… - Metabolites, 2021 - mdpi.com
Sporadic colorectal cancer is characterized by a multistep progression from normal
epithelium to precancerous low-risk and high-risk adenomas to invasive cancer. Yet, the …
epithelium to precancerous low-risk and high-risk adenomas to invasive cancer. Yet, the …
[HTML][HTML] Untargeted plasma metabolomics and risk of colorectal cancer—an analysis nested within a large-scale prospective cohort
L Vidman, R Zheng, S Bodén, A Ribbenstedt… - Cancer & …, 2023 - Springer
Background Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide,
but if discovered at an early stage, the survival rate is high. The aim of this study was to …
but if discovered at an early stage, the survival rate is high. The aim of this study was to …
Plasma metabolomic profiles for colorectal cancer precursors in women
How metabolome changes influence the early process of colorectal cancer (CRC)
development remains unknown. We conducted a 1: 2 matched nested case–control study to …
development remains unknown. We conducted a 1: 2 matched nested case–control study to …
[HTML][HTML] The application of metabolomics in recent colorectal cancer studies: a state-of-the-art review
Simple Summary Colorectal Cancer (CRC) is one of the leading causes of cancer-related
death in the United States. Current diagnosis techniques are either highly invasive or lack …
death in the United States. Current diagnosis techniques are either highly invasive or lack …