Agonist activation of central 5‐HT2A receptors results in diverse effects, such as
hallucinations and changes of consciousness. Recent findings indicate that activation of the …

A 5‐HT3 receptor agonist based on a benzamide scaffold was identified in a screening of a
small commercial compound library, and an elaborate SAR study originating from this hit …

N-Benzyl substitution of 5-HT2A receptor agonists of the phenethylamine structural class of
psychedelics (such as 4-bromo-2, 5-dimethoxyphenethylamine, often referred to as 2C-B) …

Introduction: The 5-HT1A receptors are implicated in mood disorders (anxiety, depression),
in cognition, and in modulation of pain. Nearly 30 years of research in this field, there is still …

5-HT (2) receptors mediate a large array of physiological and behavioral functions in
humans via three distinct subtypes: 5-HT (2A), 5-HT (2B) and 5-HT (2C). While selective 5 …

Phenylalkylamines such as 1-(4-bromo-2, 5-dimethoxyphenyl)-2-aminopropane (DOB; 1a)
and its corresponding iodo derivative DOI (2) are commonly used 5-HT2 serotonin agonists …

The present paper concerns the influence of conformational parameters on the recognition
by rat 5-HT1A receptors of derivatives 4-[3-(5-methoxy-1, 2, 3, 4-tetrahydronaphthalen-1-yl) …

5-HT3 receptors are members of the Cys-loop family of ligand-gated ion channels, and, like
most members of this family, there are multiple subunits that can contribute to functional …

The pharmacological profile of a series of (±)‐2, 5‐dimethoxy‐4‐(X)‐phenylisopropylamines
(X= I, Br, NO2, CH3, or H) and corresponding phenylethylamines, was determined in …

The serotonin receptor subtype 5-HT1A was one of the first serotonin receptor subtypes
pharmacologically characterized. Over the last twenty years the 5-HT1A receptor has been …