In eukaryotic cells, most mRNAs are exported from the nucleus by the transcription export
(TREX) complex, which is loaded onto mRNAs after their splicing and capping. We have …

Nuclear export of mRNAs is a crucial step in the regulation of gene expression, linking
transcription in the nucleus to translation in the cytoplasm. Although important components …

Transport of messenger RNA (mRNA) from the nucleus to the cytoplasm is an essential step
of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of …

Recent advances have led to a new understanding of how mRNAs are exported from the
nucleus to the cytoplasm. This process requires a heterodimeric mRNA export receptor that …

The REF family of evolutionarily conserved heterogeneous ribonucleoprotein (hnRNP)-like
proteins consists of one central RNP-type RNA binding domain flanked by Arg–Gly-rich …

Previous studies have led to the view that mRNAs are transported from the nucleus to the
cytoplasm by machinery that is conserved from yeast to humans. Moreover, this machinery is …

The transport of RNA molecules from the nucleus to the cytoplasm is fundamental for gene
expression. The different RNA species that are produced in the nucleus are exported …

Our understanding of protein export from the nucleus to the cytoplasm has been advanced
recently by the discovery of active, signal-mediated export pathways. Nuclear export signals …

Recent studies have established that nuclear export of mRNAs is functionally coupled to
different steps in gene expression processes, such as transcription, splicing, 3'-end …

Fully processed mRNAs are exported to the cytoplasm where they direct protein synthesis. A
general feature of mRNA export is that it is an active, receptor-mediated process. The mRNA …