Cutaneous toxicity as a predictive biomarker for clinical outcome in patients receiving anticancer therapy

AK Rzepecki, H Cheng, BN McLellan - Journal of the American Academy of …, 2018 - Elsevier
The relationship between treatment outcome and cutaneous toxicity induced by anticancer
therapy has gained attention in the past decade. In this article, we have provided an …

Dermatologic adverse events of systemic anticancer therapies: cytotoxic chemotherapy, targeted therapy, and immunotherapy

A Deutsch, NR Leboeuf, ME Lacouture… - American Society of …, 2020 - ascopubs.org
Over the past 2 decades, rapid advancement in systemic anticancer therapeutics has led to
astounding improvement in survival rates of patients with cancer. However, this celebrated …

Dermatologic challenges in cancer patients and survivors

R Agha, K Kinahan, CL Bennett, ME Lacouture - Oncology, 2007 - search.proquest.com
The increased approval of anticancer agents has led to unprecedented results, with
improved quality of life and longer survival times, resulting in millions of individuals living …

Cutaneous adverse reactions of anticancer agents

S Kaul, BH Kaffenberger, JN Choi… - Dermatologic …, 2019 - derm.theclinics.com
Conventional anticancer agents target rapidly dividing cells, which explains the common
adverse effects (AEs) seen in organ systems with a dominant population of proliferative …

Dermatologic toxicities to immune checkpoint inhibitor therapy: A review of histopathologic features

SR Ellis, AT Vierra, JW Millsop, ME Lacouture… - Journal of the American …, 2020 - Elsevier
Antineoplastic agents that use the immune system have revolutionized cancer treatment.
Specifically, implementation of immune checkpoint inhibitors, monoclonal antibodies that …

Skin toxicity of targeted cancer agents: mechanisms and intervention

VR Belum, H Fontanilla Patel, ME Lacouture… - Future …, 2013 - Taylor & Francis
In recent years, targeted agents have rapidly evolved as effective tools in the clinical
management of a broad range of malignant diseases. These agents disrupt molecular …

Dermatologic toxicities to targeted cancer therapy: shared clinical and histologic adverse skin reactions

JL Curry, CA Torres‐Cabala, KB Kim… - International journal …, 2014 - Wiley Online Library
Background Dermatologic toxicities (DT) to targeted cancer therapy may present as
inflammatory dermatoses, keratoses, and as benign and malignant squamous proliferations …

Cutaneous reactions to targeted therapy

JJ Lee, D Kroshinsky, MP Hoang - The American Journal of …, 2017 - journals.lww.com
Over the past decade, numerous targeted therapeutic agents have become available for
clinical use in the oncologic setting with the hopes of realizing personalized cancer …

The emergence of supportive oncodermatology: the study of dermatologic adverse events to cancer therapies

Y Balagula, ST Rosen, ME Lacouture - Journal of the American Academy …, 2011 - Elsevier
Cancer therapies have led to remarkable results due to improved toxicity profiles and effects
on survival. While these medical, surgical, and radiation protocols are chiefly responsible for …

Cutaneous reactions related to systemic immunomodulators and targeted therapeutics

LA Hammond-Thelin - Dermatologic clinics, 2008 - Elsevier
The arrival of targeted therapeutics into the oncology clinic, while enthusiastically
anticipated, introduced the oncologist to dermatologic events that can pose challenging …