Microfluidic formulation of nanoparticles for biomedical applications

SJ Shepherd, D Issadore, MJ Mitchell - Biomaterials, 2021 - Elsevier
Nanomedicine has made significant advances in clinical applications since the late-20th
century, in part due to its distinct advantages in biocompatibility, potency, and novel …

[HTML][HTML] Microfluidics technology for the design and formulation of nanomedicines

E Jaradat, E Weaver, A Meziane, DA Lamprou - Nanomaterials, 2021 - mdpi.com
In conventional drug administration, drug molecules cross multiple biological barriers,
distribute randomly in the tissues, and can release insufficient concentrations at the desired …

Microfluidic technologies for accelerating the clinical translation of nanoparticles

PM Valencia, OC Farokhzad, R Karnik… - Nano-enabled medical …, 2020 - taylorfrancis.com
This chapter highlights the advances in microfluidic systems that can synthesize libraries of
nanoparticles in a well-controlled, reproducible and high-throughput manner. In fact …

Microfluidic methods for fabrication and engineering of nanoparticle drug delivery systems

L Zhang, Q Chen, Y Ma, J Sun - ACS Applied Bio Materials, 2019 - ACS Publications
Microfluidic technologies with precise fluid control and rapid microscale mixing have
attracted widespread interest in the fabrication and engineering of nanomaterials for drug …

Microfluidic nanoparticles for drug delivery

Y Liu, G Yang, Y Hui, S Ranaweera, CX Zhao - Small, 2022 - Wiley Online Library
Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades.
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …

Microfluidics in nanoparticle drug delivery; From synthesis to pre-clinical screening

J Ahn, J Ko, S Lee, J Yu, YT Kim, NL Jeon - Advanced drug delivery reviews, 2018 - Elsevier
Microfluidic technologies employ nano and microscale fabrication techniques to develop
highly controllable and reproducible fluidic microenvironments. Utilizing microfluidics, lead …

Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation

S Gimondi, H Ferreira, RL Reis, NM Neves - ACS nano, 2023 - ACS Publications
The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of
diseases for which conventional therapies present serious limitations. Additionally, NPs can …

[HTML][HTML] Design of functional nanoparticles by microfluidic platforms as advanced drug delivery systems for cancer therapy

A Fabozzi, F Della Sala, M di Gennaro, M Barretta… - Lab on a Chip, 2023 - pubs.rsc.org
Nanoparticle systems are functional carriers that can be used in the cancer therapy field for
the delivery of a variety of hydrophobic and/or hydrophilic drugs. Recently, the advent of …

Microfluidics: a transformational tool for nanomedicine development and production

S Garg, G Heuck, S Ip, E Ramsay - Journal of drug targeting, 2016 - Taylor & Francis
Microfluidic devices are mircoscale fluidic circuits used to manipulate liquids at the nanoliter
scale. The ability to control the mixing of fluids and the continuous nature of the process …

Microfluidic systems for manufacturing of microparticle-based drug-delivery systems: design, construction, and operation

N Yonet-Tanyeri, M Amer, SC Balmert… - ACS biomaterials …, 2022 - ACS Publications
Particles synthesized from biodegradable polymers hold great potential as controlled drug
delivery systems. Continuous flow platforms based on microfluidics offer attractive …