miRNAs as biomarkers for early cancer detection and their application in the development of new diagnostic tools

LJ Galvão-Lima, AHF Morais, RAM Valentim… - Biomedical engineering …, 2021 - Springer
Over the last decades, microRNAs (miRNAs) have emerged as important molecules
associated with the regulation of gene expression in humans and other organisms …

MicroRNA in carcinogenesis & cancer diagnostics: a new paradigm

J Ahmad, SE Hasnain, MA Siddiqui… - Indian Journal of …, 2013 - journals.lww.com
Abstract MicroRNAs (miRNAs) are small 22-25 nucleotides long non-coding RNAs, that are
conserved during evolution, and control gene expression in metazoan animals, plants …

[HTML][HTML] MicroRNAs: potential biomarkers for diagnosis and prognosis of different cancers

PC Sharma, A Gupta - Translational cancer research, 2020 - ncbi.nlm.nih.gov
A thorough understanding of the tumor environment and underlying genetic factors helps in
the better formulation of cancer management strategies. Availability of efficient diagnostic …

The role of microRNAs in cancer: diagnostic and prognostic biomarkers and targets of therapies

LR Corsini, G Bronte, M Terrasi, V Amodeo… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: miRNAs are noncoding RNAs that target specific mRNA with subsequent
regulation of particular genes, implicated in various biological processes. In cancer, miRNAs …

miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis

CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

microRNA biosensors: Opportunities and challenges among conventional and commercially available techniques

T Kilic, A Erdem, M Ozsoz, S Carrara - Biosensors and Bioelectronics, 2018 - Elsevier
As being the most extensively studied, non-coding, evolutionary conserved, post-
transcriptional gene regulators of genome, microRNAs (miRNAs) have taken great attention …

Validation of miRNAs as breast cancer biomarkers with a machine learning approach

O Rehman, H Zhuang, A Muhamed Ali, A Ibrahim, Z Li - Cancers, 2019 - mdpi.com
Certain small noncoding microRNAs (miRNAs) are differentially expressed in normal tissues
and cancers, which makes them great candidates for biomarkers for cancer. Previously, a …

[PDF][PDF] MicroRNA biogenesis, functionality and cancer relevance

B Kusenda, M Mraz, J Mayer… - Biomed Pap Med Fac …, 2006 - researchgate.net
Background: MicroRNAs (miRNA) are small non–coding RNAs that negatively regulate
gene expression in a sequence–specific manner. Post–transcriptional silencing of target …

miRNAs in cancer (review of literature)

B Smolarz, A Durczyński, H Romanowicz… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are short, noncoding, single-stranded RNA molecules that regulate
gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the …

Micro-RNAs: The new potential biomarkers in cancer diagnosis, prognosis and cancer therapy

B Mansoori, A Mohammadi, S Shirjang… - Cellular and Molecular …, 2015 - cellmolbiol.org
MicroRNAs (miRNAs) are a large class of small noncoding RNAs approximately 22
nucleotides in length. They are the main regulators of gene expression, regulating specific …