Several options for cancer prevention are available for women with a BRCA1 or BRCA2
mutation, including prophylactic surgery, chemoprevention and screening. The authors …

The purpose of our study was to review the evidence for the efficacy of surveillance for early
detection, bilateral prophylactic mastectomy, prophylactic oophorectomy and …

Background: In women with a family history of breast cancer, bilateral prophylactic
mastectomy is associated with a decreased risk of subsequent breast cancer of …

Background Women with a BRCA1 or BRCA2 mutation face high risks of breast and ovarian
cancer. In the current study, we report on uptake of cancer screening and risk-reduction …

There are two mutations in BRCA1 and one in BRCA2, which are present in up to 2.5% of
Jewish women. Population genetic testing for Jewish women has been proposed; however …

Objective: Women who are carriers of BRCA gene mutations have an elevated lifetime risk
of developing breast or ovarian cancer. Although a number of risk-reducing options are …

A systematic review of the literature was conducted to assess the outcomes of preventive
interventions (prophylactic surgery, intensive cancer screening, and chemoprevention) in …

BACKGROUND. Women who are at increased risk for breast and ovarian cancers,
especially BRCA1 and BRCA2 mutation carriers, face a myriad of risk‐reduction options …

Comparative effectiveness research has become an integral part of health care planning in
most developed countries. In a simulated cohort of women, aged 30–65, who tested positive …

Purpose Data on the efficacy of bilateral prophylactic mastectomy for breast cancer risk
reduction in women with BRCA1 and BRCA2 (BRCA1/2) mutations are limited, despite the …