Continuing improvements in analytical technology along with an increased interest in
performing comprehensive, quantitative metabolic profiling, is leading to increased interest …

With continuing improvements in analytical technology and an increased interest in
comprehensive metabolic profiling of biofluids and tissues, there is a growing need to …

Abstract The Human Metabolome Database (HMDB) is currently the most complete and
comprehensive curated collection of human metabolite and human metabolism data in the …

Highlights•Metabolomics provides a functional read-out of the physiological status of an
organism.•A precise (dynamic) description of the clinical phenotype is missing for complex …

Abstract The Human Metabolome Database (HMDB, http://www. hmdb. ca) is a richly
annotated resource that is designed to address the broad needs of biochemists, clinical …

The human metabolome provides a direct physiological read-out of an individual's actual
health state and includes biomarkers that may predict disease or response to a treatment …

Metabolomics is the untargeted measurement of the metabolome, which is composed of the
complement of small molecules detected in a biological sample. As such, metabolomic …

Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …

Metabolomics, which is the metabolites profiling in biological matrices, is a key tool for
biomarker discovery and personalized medicine and has great potential to elucidate the …

Analytical and biological variability are issues of central importance to human metabolomics
studies. Here both types of variation are examined in human plasma and cerebrospinal fluid …