Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

EE Calle, R Kaaks - Nature Reviews Cancer, 2004 - nature.com
The prevalence of obesity is rapidly increasing globally. Epidemiological studies have
associated obesity with a range of cancer types, although the mechanisms by which obesity …

Obesity and cancer risk: Emerging biological mechanisms and perspectives

KI Avgerinos, N Spyrou, CS Mantzoros, M Dalamaga - Metabolism, 2019 - Elsevier
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

Association of obesity-related metabolic disruptions with cancer risk and outcome

AE Lohmann, PJ Goodwin, RT Chlebowski… - Journal of Clinical …, 2016 - ascopubs.org
Over the past 40 years, the prevalence of obesity has increased epidemically worldwide,
which raises significant concerns regarding public health and the associated economic …

Obesity and risk of cancer: an introductory overview

T Pischon, K Nimptsch - Obesity and cancer, 2016 - Springer
The prevalence of obesity has increased substantially in the past in almost all countries of
the world, and a further increase is expected for the future. Besides the well-established …

Physiological and environmental factors affecting cancer risk and prognosis in obesity

PFS Etet, L Vecchio, AHN Kamdje, PN Mimche… - Seminars in Cancer …, 2023 - Elsevier
Obesity results from a chronic excessive accumulation of adipose tissue due to a long-term
imbalance between energy intake and expenditure. Available epidemiological and clinical …

[HTML][HTML] Obesity and cancer: a current overview of epidemiology, pathogenesis, outcomes, and management

S Pati, W Irfan, A Jameel, S Ahmed, RK Shahid - Cancers, 2023 - mdpi.com
Simple Summary Obesity has been linked to several common cancers including breast,
colorectal, esophageal, kidney, gallbladder, uterine, pancreatic, and liver cancer. Obesity …

Obesity as a major risk factor for cancer

G De Pergola, F Silvestris - Journal of obesity, 2013 - Wiley Online Library
The number of cancer cases caused by being obese is estimated to be 20% with the
increased risk of malignancies being influenced by diet, weight change, and body fat …

Obesity and cancer: local and systemic mechanisms

NM Iyengar, CA Hudis… - Annual review of …, 2015 - annualreviews.org
Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …

Obesity and cancer mechanisms: cancer metabolism

BD Hopkins, MD Goncalves, LC Cantley - Journal of clinical oncology, 2016 - ascopubs.org
Obesity is a risk factor for cancer development and is associated with poor prognosis in
multiple tumor types. The positive energy balance linked with obesity induces a variety of …

[HTML][HTML] Obesity and cancer: mechanistic insights from transdisciplinary studies

EH Allott, SD Hursting - Endocrine-related cancer, 2015 - erc.bioscientifica.com
Obesity is associated with a range of health outcomes that are of clinical and public health
significance, including cancer. Herein, we summarize epidemiologic and preclinical …