[HTML][HTML] Interconnections between inflammageing and immunosenescence during ageing

T Teissier, E Boulanger, LS Cox - Cells, 2022 - mdpi.com
Acute inflammation is a physiological response to injury or infection, with a cascade of steps
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …

An update on inflamm‐aging: mechanisms, prevention, and treatment

S Xia, X Zhang, S Zheng, R Khanabdali… - Journal of …, 2016 - Wiley Online Library
Inflamm‐aging is a challenging and promising new branch of aging‐related research fields
that includes areas such as immunosenescence. Increasing evidence indicates that inflamm …

Immune system, cell senescence, aging and longevity-inflamm-aging reappraised

S Salvioli, D Monti, C Lanzarini, M Conte… - Current …, 2013 - ingentaconnect.com
Inflamm-aging, that is the age-associated inflammatory status, is considered one of the most
striking consequences of immunosenescence, as it is believed to be linked to the majority of …

Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?

A Santoro, E Bientinesi, D Monti - Ageing research reviews, 2021 - Elsevier
During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

[HTML][HTML] Immunosenescence and inflamm-aging as two sides of the same coin: friends or foes?

T Fulop, A Larbi, G Dupuis, A Le Page… - Frontiers in …, 2018 - frontiersin.org
The immune system is the most important protective physiological system of the organism. It
has many connections with other systems and is, in fact, often considered as part of the …

[HTML][HTML] Age and age-related diseases: role of inflammation triggers and cytokines

IM Rea, DS Gibson, V McGilligan… - Frontiers in …, 2018 - frontiersin.org
Cytokine dysregulation is believed to play a key role in the remodeling of the immune
system at older age, with evidence pointing to an inability to fine-control systemic …

[HTML][HTML] Immune system modulation in aging: Molecular mechanisms and therapeutic targets

B Cisneros, I García-Aguirre, J Unzueta… - Frontiers in …, 2022 - frontiersin.org
The function of the immune system declines during aging, compromising its response
against pathogens, a phenomenon termed as “immunosenescence.” Alterations of the …

[HTML][HTML] Aging and chronic inflammation: highlights from a multidisciplinary workshop

D Saavedra, AL Añé-Kourí, N Barzilai, C Caruso… - Immunity & …, 2023 - Springer
Aging is a gradual, continuous series of natural changes in biological, physiological,
immunological, environmental, psychological, behavioral, and social processes. Aging …

[HTML][HTML] The role of immune cells in oxi-inflamm-aging

I Martinez de Toda, N Ceprián, E Díaz-Del Cerro… - Cells, 2021 - mdpi.com
Aging is the result of the deterioration of the homeostatic systems (nervous, endocrine, and
immune systems), which preserve the organism's health. We propose that the age-related …

[PDF][PDF] Inflammaging 2018: an update and a model

C Franceschi, A Zaikin, S Gordleeva… - Seminars in …, 2018 - discovery.ucl.ac.uk
'Inflammaging'refers to the chronic, low-grade inflammation that characterizes aging. The
conceptualization of inflammaging, resulting from the convergence of studies on the …