White and brown adipose tissues are hypervascularized and the adipose vasculature
displays phenotypic and functional plasticity to coordinate with metabolic demands of …

Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic
metabolic homeostasis. Additionally, adipose tissue is a pivotal regulator of cardiovascular …

The growth and function of tissues are critically dependent on their vascularization. Adipose
tissue is capable of expanding many-fold during adulthood, therefore requiring the formation …

While most tissues exhibit their greatest growth during development, adipose tissue is
capable of additional massive expansion in adults. Adipose tissue expandability is …

Obesity is a worldwide health problem, and as its prevalence increases, so does the burden
of obesity-associated co-morbidities like type 2 diabetes or cardiovascular diseases (CVDs) …

Current pharmacotherapeutic options for treating obesity and related metabolic disorders
remain limited and ineffective. Emerging evidence shows that modulators of angiogenesis …

Obesity is an ever-increasing phenomenon, with 42% of Americans being considered obese
(BMI≥ 30) and 9.2% being considered morbidly obese (BMI≥ 40) as of 2016. With obesity …

Obesity is a common disorder and related diseases, such as diabetes, atherosclerosis,
hypertension, cardiovascular disease and cancer, are a major cause of mortality and …

With an increasing incidence of obesity worldwide, rational strategies are needed to control
adipogenesis. Growth of any tissue requires the formation of a functional and mature …

There is a close anatomical and functional relationship between adipose tissue and blood
vessels. The crosstalk between these two organs is vital to both metabolic and vascular …