Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis
AW Orr, NE Hastings, BR Blackman… - Journal of vascular …, 2010 - karger.com
Vascular smooth muscle cell (SMC) phenotypic modulation plays a key role in
atherosclerosis and is classically defined as a switch from a 'contractile'phenotype to a …
atherosclerosis and is classically defined as a switch from a 'contractile'phenotype to a …
Vascular smooth muscle cell in atherosclerosis
DA Chistiakov, AN Orekhov, YV Bobryshev - Acta physiologica, 2015 - Wiley Online Library
Vascular smooth muscle cells (VSMC s) exhibit phenotypic and functional plasticity in order
to respond to vascular injury. In case of the vessel damage, VSMC s are able to switch from …
to respond to vascular injury. In case of the vessel damage, VSMC s are able to switch from …
Smooth muscle cell phenotypic switching in atherosclerosis
D Gomez, GK Owens - Cardiovascular research, 2012 - academic.oup.com
Smooth muscle cells (SMCs) possess remarkable phenotypic plasticity that allows rapid
adaptation to fluctuating environmental cues, including during development and progression …
adaptation to fluctuating environmental cues, including during development and progression …
Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development
H Hao, G Gabbiani… - … , thrombosis, and vascular …, 2003 - Am Heart Assoc
During atheromatous plaque formation or restenosis after angioplasty, smooth muscle cells
(SMCs) migrate from the media toward the intima, where they proliferate and undergo …
(SMCs) migrate from the media toward the intima, where they proliferate and undergo …
Role of mechanical strain in regulation of differentiation of vascular smooth muscle cells
GK Owens - Circulation research, 1996 - Am Heart Assoc
The differentiated vascular smooth muscle cell (SMC) is a highly specialized cell that
expresses a unique repertoire of contractile proteins, ion channels, membrane receptors …
expresses a unique repertoire of contractile proteins, ion channels, membrane receptors …
Vascular smooth muscle cells in atherosclerosis
MR Bennett, S Sinha, GK Owens - Circulation research, 2016 - Am Heart Assoc
The historical view of vascular smooth muscle cells (VSMCs) in atherosclerosis is that
aberrant proliferation of VSMCs promotes plaque formation, but that VSMCs in advanced …
aberrant proliferation of VSMCs promotes plaque formation, but that VSMCs in advanced …
Smooth muscle cell heterogeneity: patterns of gene expression in vascular smooth muscle cells in vitro and in vivo
CM Shanahan, PL Weissberg - Arteriosclerosis, thrombosis, and …, 1998 - Am Heart Assoc
Early morphological and biochemical studies indicated that vascular smooth muscle cells
(VSMCs) exhibited two distinct phenotypes and that a change from the contractile to the …
(VSMCs) exhibited two distinct phenotypes and that a change from the contractile to the …
Smooth muscle cell fate and plasticity in atherosclerosis
S Allahverdian, C Chaabane, K Boukais… - Cardiovascular …, 2018 - academic.oup.com
Current knowledge suggests that intimal smooth muscle cells (SMCs) in native
atherosclerotic plaque derive mainly from the medial arterial layer. During this process …
atherosclerotic plaque derive mainly from the medial arterial layer. During this process …
Role of smooth muscle cells in the initiation and early progression of atherosclerosis
AC Doran, N Meller, CA McNamara - … , thrombosis, and vascular …, 2008 - Am Heart Assoc
The initiation of atherosclerosis results from complex interactions of circulating factors and
various cell types in the vessel wall, including endothelial cells, lymphocytes, monocytes …
various cell types in the vessel wall, including endothelial cells, lymphocytes, monocytes …
Emerging regulators of vascular smooth muscle cell function in the development and progression of atherosclerosis
JL Johnson - Cardiovascular research, 2014 - academic.oup.com
After a period of relative senescence in the field of vascular smooth muscle cell (VSMC)
research with particular regards to atherosclerosis, the last few years has witnessed a …
research with particular regards to atherosclerosis, the last few years has witnessed a …