Biflavonoids are a kind of polyphenol compounds with numerous biological functions.
However, the potential inhibitory activities of biflavonoids on α-glucosidase are yet unknown …

Flavonoid compounds have anti-diabetic activity, which can control blood glucose levels by
inhibiting α-glucosidase activity. In this paper, the inhibition mechanisms between four …

Flavonoids are known to play a role in hypoglycemia by inhibiting α-glucosidase. However,
their interaction mechanism with α-glucosidase still needs to be elaborated. In this study, the …

The structure–activity relationship and inhibitory mechanism of flavonols on α-glucosidase
were studied by inhibition kinetics, multispectral study, and molecular docking. The flavonols …

Inhibition of α-glucosidase activity may suppress postprandial hyperglycemia. The inhibition
kinetic analysis showed that apigenin reversibly inhibited α-glucosidase activity with an IC50 …

Abstract α-Glucosidase is a key enzyme related to starch digestion and type-2 diabetes. In
the present study, the inhibition effect and the underlying mechanism of Chinese bayberry …

Abstract α-Glucosidase is a therapeutic target for diabetes mellitus, and α-glucosidase
inhibitors play a vital role in the treatments for the disease. As a kind of potentially safer α …

The inhibition of α-glucosidase activity is a prospective approach to prevent postprandial
hyperglycemia. As two flavonoids extracted from citrus fruits, eriocitrin and eriodictyol have …

The inhibition properties of 10 tea polyphenols against α-glucosidase were studied through
inhibition assay, inhibition kinetics, fluorescence quenching and molecular docking. It was …

α-Glucosidase (AG) has always been an indispensable drug target for the treatment of type
2 diabetes. Herein, an integrated method consisting of enzyme kinetics, multi-spectroscopy …