Genome binning of viral entities from bulk metagenomics data
Despite the accelerating number of uncultivated virus sequences discovered in
metagenomics and their apparent importance for health and disease, the human gut virome …
metagenomics and their apparent importance for health and disease, the human gut virome …
Phage-inclusive profiling of human gut microbiomes with Phanta
Due to technical limitations, most gut microbiome studies have focused on prokaryotes,
overlooking viruses. Phanta, a virome-inclusive gut microbiome profiling tool, overcomes the …
overlooking viruses. Phanta, a virome-inclusive gut microbiome profiling tool, overcomes the …
Improved metagenome binning and assembly using deep variational autoencoders
Despite recent advances in metagenomic binning, reconstruction of microbial species from
metagenomics data remains challenging. Here we develop variational autoencoders for …
metagenomics data remains challenging. Here we develop variational autoencoders for …
Metaviral SPAdes: assembly of viruses from metagenomic data
D Antipov, M Raiko, A Lapidus, PA Pevzner - Bioinformatics, 2020 - academic.oup.com
Motivation Although the set of currently known viruses has been steadily expanding, only a
tiny fraction of the Earth's virome has been sequenced so far. Shotgun metagenomic …
tiny fraction of the Earth's virome has been sequenced so far. Shotgun metagenomic …
DeePhage: distinguishing virulent and temperate phage-derived sequences in metavirome data with a deep learning approach
Background Prokaryotic viruses referred to as phages can be divided into virulent and
temperate phages. Distinguishing virulent and temperate phage–derived sequences in …
temperate phages. Distinguishing virulent and temperate phage–derived sequences in …
VirFinder: a novel k-mer based tool for identifying viral sequences from assembled metagenomic data
Background Identifying viral sequences in mixed metagenomes containing both viral and
host contigs is a critical first step in analyzing the viral component of samples. Current tools …
host contigs is a critical first step in analyzing the viral component of samples. Current tools …
CONCOCT: clustering contigs on coverage and composition
J Alneberg, BS Bjarnason, I de Bruijn… - arXiv preprint arXiv …, 2013 - arxiv.org
Metagenomics enables the reconstruction of microbial genomes in complex microbial
communities without the need for culturing. Since assembly typically results in fragmented …
communities without the need for culturing. Since assembly typically results in fragmented …
Metagenomic analysis reveals unexplored diversity of archaeal virome in the human gut
The human gut microbiome has been extensively explored, while the archaeal viruses
remain largely unknown. Here, we present a comprehensive analysis of the archaeal …
remain largely unknown. Here, we present a comprehensive analysis of the archaeal …
VIBRANT: automated recovery, annotation and curation of microbial viruses, and evaluation of viral community function from genomic sequences
K Kieft, Z Zhou, K Anantharaman - Microbiome, 2020 - Springer
Background Viruses are central to microbial community structure in all environments. The
ability to generate large metagenomic assemblies of mixed microbial and viral sequences …
ability to generate large metagenomic assemblies of mixed microbial and viral sequences …
vRhyme enables binning of viral genomes from metagenomes
Genome binning has been essential for characterization of bacteria, archaea, and even
eukaryotes from metagenomes. Yet, few approaches exist for viruses. We developed …
eukaryotes from metagenomes. Yet, few approaches exist for viruses. We developed …