Castration resistant-prostate cancer is largely impervious to feather hormonal therapy and
hence the outlook for patients is grim. Here we use an approach to attach the recently …

Previous study has suggested that the FABP5-PPARγ-signalling transduction pathway
gradually replaces the androgen receptor activated pathway in promoting malignant …

Fatty acid-binding protein 5 (FABP5) and androgen receptor (AR) are critical promoters of
prostate cancer. In the present study, the effects of knocking out the FABP5 or AR genes on …

Highlights•Fatty acid binding protein 5 (FABP5) is upregulated in many cancers, particularly
prostate cancer (PC).•FABP5 facilitates the delivery of fatty acids to peroxisome proliferator …

Abstract Background Prostate cancer (PCa) remains the second leading cause of cancer‐
related death among men. Taxanes, such as docetaxel and cabazitaxel are utilized in …

Prostate cancer is a leading cause of cancer-related deaths in men in the United States.
Although treatable when detected early, prostate cancer commonly transitions to an …

Previous work showed that FABP5 inhibitors suppressed the malignant progression of
prostate cancer cells, and this suppression might be achieved partially by promoting …

Early stage localized prostate cancer (PCa) has an excellent prognosis; however, patient
survival drops dramatically when PCa metastasizes. The molecular mechanisms underlying …

Fatty acid binding protein 4 (FABP4) is an abundant protein in adipocytes, and its production
is influenced by high-fat diet (HFD) or obesity. The prostate stromal microenvironment …

Abstract Background FAM3B/PANDER is a novel cytokine-like protein that induces
apoptosis in insulin-secreting beta-cells. Since in silico data revealed that FAM3B can be …