Poly (lactic‐co‐glycolic acid)(PLGA) nanoparticles (NPs) are commonly used for drug
delivery because of their favored biocompatibility and suitability for sustained and controlled …

We reexamined the cellular drug delivery mechanism by poly (lactic-co-glycolic acid)
nanoparticles (PLGA NPs) to determine their utility and limitations as an intracellular drug …

Highlights•PLGA-hybrid nanoparticles are emerging as a versatile drug delivery
vehicle.•Their tunable properties and surface characteristics offer therapeutic/diagnostic …

Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …

Nanocarriers formulated with the US Food and Drug Administration-approved biocompatible
and biodegradable polymer poly (lactic-co-glycolic acid)(PLGA) are being widely explored …

The use of poly (lactic-co-glycolic acid)(PLGA)-based nanocarriers presents several major
challenges, including their synthetic hydrophobic surface, low transfection efficiency, short …

Over the years, issues associated with non-biodegradable polymers have paved the way for
biodegradable polymers in the domain of pharmaceutical and biomedical sciences. Poly …

Numerous human disorders can benefit from targeted, intravenous (IV) drug delivery.
Polymeric nanoparticles have been designed to undergo systemic circulation and deliver …

Confocal Raman Microscopy (CRM) is used to study the cell internalization of poly (lactide-
co-glycolide)(PLGA) nanoparticles (NPs) fabricated by emulsion techniques with either poly …

Macrophages possess an innate ability to scavenge heterogenous objects from the systemic
circulation and to regulate inflammatory diseases in various organs via cytokine production …