Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription
factor that is involved in lipid metabolism of various tissues. Different metabolites of fatty …

Lipid metabolic diseases have substantial morbidity and mortality rates, posing a significant
threat to human health. PPARα, a member of the peroxisome proliferator-activated receptors …

PEROXISOME proliferator-activated receptors (PPARs) are ligand-activated transcriptional
factors belonging to superfamily of nuclear hormone receptors related to retinoid, steroid …

The metabolic syndrome, also known as 'syndrome X'or 'insulin-resistance syndrome', has
emerged as a constellation of risk factors that markedly increase the risk of Type 2 diabetes …

Cardiovascular disease is the leading cause of morbidity and mortality world-wide. The
burden of disease is also increasing as a result of the global epidemics of diabetes and …

It has been more than 36 years since peroxisome proliferator-activated receptors (PPARs)
were first recognized as enhancers of peroxisome proliferation. Consequently, many studies …

Obesity is a growing threat to global health by virtue of its association with insulin resistance,
glucose intolerance, hypertension, and dyslipidemia, collectively known as the metabolic …

Abstract Purpose of Review Full and partial synthetic agonists targeting the transcription
factor PPARγ are contained in FDA-approved insulin-sensitizing drugs and used for the …

Among individuals with diabetes mellitus, cardiovascular disease remains the leading cause
of death, despite the many treatment modalities that have been developed over time. The …

Three members of the peroxisome proliferator-activated receptor (PPAR) family, PPARα,
PPARγ, and PPARβ/δ, have been investigated widely over the past few decades. Although …