Among the four G protein–coupled receptors (H1–H4) identified as mediators of the biologic
effects of histamine, the H3 receptor (H3R) is distinguished for its almost exclusive …

Constitutive activity has been mainly recorded for numerous overexpressed and/or mutated
receptors. The histamine H 3 receptor (H 3 R) is a target of choice to study the physiological …

The cloning of the histamine H3 receptor (H3R) cDNA in 1999 by Lovenberg et al.[10]
allowed detailed studies of its molecular aspects and indicated that the H3R can activate …

Histamine regulates neurotransmitter release in the central and peripheral nervous systems
through H3 presynaptic receptors. The existence of the histamine H3 receptor was …

The identification of histamine H3 (H3R) and H4 (H4R) receptors some years ago revived
interest in histamine research and exposed attractive perspectives for the potential …

Since the cloning of the histamine H3 receptor cDNA in 1999 by Lovenberg and co-workers,
this histamine receptor has gained the interest of many pharmaceutical companies as a …

Starting from the sequence of the human histamine H3 receptor (hH3R) cDNA, we have
cloned the corresponding rat cDNA. Whereas the two deduced proteins show 93.5% overall …

The recently identified histamine H 4 receptor has revealed a potential new complexity for
the role of histamine in the immune system. To begin to understand the role of this receptor …

Human, guinea pig and rat histamine H3 receptors have been investigated at both
pharmacological and molecular levels in recent years. Here we report the cloning …

We described previously the cDNA cloning of three functional rat histamine H3 receptor
(rH3R) isoforms as well as the differential brain expression patterns of their corresponding …