Preparation, characterization, and pharmacological application of oral Honokiol-loaded solid lipid nanoparticles for diabetic neuropathy
Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …
Honokiol nanosuspensions: preparation, increased oral bioavailability and dramatically enhanced biodistribution in the cardio-cerebro-vascular system
M Han, X Yu, Y Guo, Y Wang, H Kuang… - Colloids and Surfaces B …, 2014 - Elsevier
Honokiol is a phytochemical component with multiple pharmacological activities, but
Honokiol's wider use has been restricted by its poor solubility. Using bovine serum albumin …
Honokiol's wider use has been restricted by its poor solubility. Using bovine serum albumin …
Preparation of honokiol nanoparticles by liquid antisolvent precipitation technique, characterization, pharmacokinetics, and evaluation of inhibitory effect on HepG2 …
W Wu, L Wang, L Wang, Y Zu, S Wang… - International Journal of …, 2018 - Taylor & Francis
Background Honokiol is a bioactive lignanoid and has been utilized in traditional Chinese
medicine for a long time. It exhibits several pharmacological properties, such as anticancer …
medicine for a long time. It exhibits several pharmacological properties, such as anticancer …
Development of nanosome-encapsulated honokiol for intravenous therapy against experimental autoimmune encephalomyelitis
YP Hsiao, HT Chen, YC Liang, TE Wang… - International Journal …, 2020 - Taylor & Francis
Background Honokiol has been reported to possess anti-inflammatory and neuroprotective
activities. However, the poor aqueous solubility of honokiol limits its clinical application for …
activities. However, the poor aqueous solubility of honokiol limits its clinical application for …
Development and biological evaluation of Gymnema sylvestre extract-loaded nonionic surfactant-based niosomes
Aim: To develop and characterize Gymnema sylvestre extract-loaded niosomes using
nonionic surfactants, and to evaluate their antihyperglycemic efficacy in comparison with the …
nonionic surfactants, and to evaluate their antihyperglycemic efficacy in comparison with the …
Poly (ɛ-caprolactone)–poly (ethylene glycol)–poly (ɛ-caprolactone)(PCL–PEG–PCL) nanoparticles for honokiol delivery in vitro
ML Gou, L Zheng, XY Peng, K Men, XL Zheng… - International journal of …, 2009 - Elsevier
In this article, poly (ɛ-caprolactone)–poly (ethylene glycol)–poly (ɛ-caprolactone)(PCL–PEG–
PCL, PCEC) nanoparticles were successfully prepared for honokiol delivery in vitro. Blank or …
PCL, PCEC) nanoparticles were successfully prepared for honokiol delivery in vitro. Blank or …
Rosuvastatin nanomicelles target neuroinflammation and improve neurological deficit in a mouse model of intracerebral hemorrhage
L Zi, W Zhou, J Xu, J Li, N Li, J Xu, C You… - International Journal …, 2021 - Taylor & Francis
Background Intracerebral hemorrhage (ICH), a devastating subtype of stroke, has a poor
prognosis. However, there is no effective therapy currently available due to its complex …
prognosis. However, there is no effective therapy currently available due to its complex …
[HTML][HTML] Apigenin-loaded solid lipid nanoparticle attenuates diabetic nephropathy induced by streptozotocin nicotinamide through Nrf2/HO-1/NF-kB signalling pathway
P Li, SNA Bukhari, T Khan, R Chitti… - International journal …, 2020 - ncbi.nlm.nih.gov
Background Apigenin is known to have a broad-spectrum efficacy in oxidative stress and
conditions due to inflammation, although weak absorption, fast metabolic rate and a fast …
conditions due to inflammation, although weak absorption, fast metabolic rate and a fast …
Phospholipid nanoformulation of thymoquinone with enhanced bioavailability: Development, characterization and anti-inflammatory activity
Thymoquinone (TQ), a potent bioactive of Nigella sativa plant, is highly hydrophobic
molecule and thus associated with poor oral bioavailability. The present work proposes the …
molecule and thus associated with poor oral bioavailability. The present work proposes the …
Core-shell hybrid liposomal vesicles loaded with panax notoginsenoside: preparation, characterization and protective effects on global cerebral ischemia/reperfusion …
J Zhang, X Han, X Li, Y Luo, H Zhao… - International journal …, 2012 - Taylor & Francis
Purpose Novel panax notoginsenoside-loaded core-shell hybrid liposomal vesicles (PNS-
HLV) were developed to resolve the restricted bioavailability of PNS and to enhance its …
HLV) were developed to resolve the restricted bioavailability of PNS and to enhance its …
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- lipid nanoparticle streptozotocin nicotinamide
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