Correlates of cognitive dysfunction in multiple sclerosis

C Heesen, KH Schulz, J Fiehler, U Von der Mark… - Brain, behavior, and …, 2010 - Elsevier
Cognitive impairment is one of the most frequent symptoms in patients with multiple
sclerosis (MS) but its underlying mechanisms are poorly understood. A number of …

A longitudinal study on fatigue, depression, and their relation to neurocognition in multiple sclerosis

H Hildebrandt, P Eling - Journal of Clinical and Experimental …, 2014 - Taylor & Francis
Aims: Fatigue and depression are two common syndromes in patients with multiple sclerosis
(MS), but their inherent relation and causes are still under debate. Method: With a …

Subjective fatigue is not associated with cognitive impairment in multiple sclerosis: cross-sectional and longitudinal analysis

SA Morrow, B Weinstock-Guttman… - Multiple Sclerosis …, 2009 - journals.sagepub.com
Background Studies in multiple sclerosis (MS) report conflicting conclusions regarding
fatigue and cognition, which may partly be due to the use of small sample sizes and frequent …

Risk factors for and management of cognitive dysfunction in multiple sclerosis

RHB Benedict, R Zivadinov - Nature Reviews Neurology, 2011 - nature.com
Cognitive impairment is common in multiple sclerosis (MS), especially when assessed by
neuropsychological tests that emphasize mental processing speed, episodic memory, and …

The impact of subjective cognitive fatigue and depression on cognitive function in patients with multiple sclerosis

D Golan, GM Doniger, K Wissemann… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: The association between subjective cognitive fatigue and objective cognitive
dysfunction in patients with multiple sclerosis (PwMS) has been studied, with conflicting …

Fatigue in multiple sclerosis: an example of cytokine mediated sickness behaviour?

C Heesen, L Nawrath, C Reich, N Bauer… - Journal of Neurology …, 2006 - jnnp.bmj.com
Background: Fatigue is a major complaint of multiple sclerosis (MS) patients. However, little
is known about its pathophysiological mechanisms. Evidence from chronic fatigue syndrome …

Is there a cognitive signature for MS-related fatigue?

K Hanken, P Eling… - Multiple Sclerosis Journal, 2015 - journals.sagepub.com
The compensatory approach of fatigue argues that it is a state caused by task load. The
neuropsychiatric approach argues that fatigue is a trait (like depression), unrelated to …

Cognitive dysfunction in multiple sclerosis

J Guimarães, MJ Sá - Frontiers in neurology, 2012 - frontiersin.org
In Multiple Sclerosis (MS) prevalence studies of community and clinical samples, indicate
that 45–60% of patients are cognitively impaired. These cognitive dysfunctions have been …

Apathy/depression, but not subjective fatigue, is related with cognitive dysfunction in patients with multiple sclerosis

M Niino, N Mifune, T Kohriyama, M Mori, T Ohashi… - BMC neurology, 2014 - Springer
Background Cognitive impairment could affect quality of life for patients with multiple
sclerosis (MS), and cognitive function may be correlated with several factors such as …

Fatigue and declines in cognitive functioning in multiple sclerosis

LB Krupp, LE Elkins - Neurology, 2000 - AAN Enterprises
Objective: To determine whether cognitive fatigue, defined as a decline in cognitive
performance over a single testing session, could be identified in MS. Methods: Forty-five …