Safety challenges and application strategies for the use of dendrimers in medicine

X Li, A Naeem, S Xiao, L Hu, J Zhang, Q Zheng - Pharmaceutics, 2022 - mdpi.com
Dendrimers are used for a variety of applications in medicine but, due to their host–guest
and entrapment characteristics, are particularly used for the delivery of genes and drugs …

Dendrimer biocompatibility and toxicity

R Duncan, L Izzo - Advanced drug delivery reviews, 2005 - Elsevier
The field of biomedical dendrimers is still in its infancy, but the explosion of interest in
dendrimers and dendronised polymers as inherently active therapeutic agents, as vectors …

Potential application of dendrimers in drug delivery: A concise review and update

SK Parajapati, SD Maurya, MK Das… - Journal of Drug …, 2016 - jddtonline.info
This review gives concise information about the application of dendrimers in the field of drug
delivery. Due to their unique architecture these have improved physical and chemical …

Dendrimers in drug delivery, diagnosis and therapy: basics and potential applications

SK Prajapati, SD Maurya, MK Das, VK Tilak… - Journal of Drug …, 2016 - jddtonline.info
This review gives concise information about the dendrimers, properties, synthesis and
application in drug delivery, diagnosis and therapy. Due to their unique architecture these …

Emerging opportunities in the biomedical applications of dendrimers

AS Abd-El-Aziz, C Agatemor - Journal of Inorganic and Organometallic …, 2018 - Springer
The medical field remains challenged with many unmet needs, prompting rigorous research
for solutions. Dendrimers are emerging as innovative solutions to many unmet clinical …

Dendrimers in medicine: therapeutic concepts and pharmaceutical challenges

L Wu, M Ficker, JB Christensen… - Bioconjugate …, 2015 - ACS Publications
Dendrimers are three-dimensional macromolecular structures originating from a central core
molecule and surrounded by successive addition of branching layers (generation). These …

Understanding specific and nonspecific toxicities: a requirement for the development of dendrimer‐based pharmaceuticals

DQ McNerny, PR Leroueil… - Wiley Interdisciplinary …, 2010 - Wiley Online Library
Dendrimer conjugates for pharmaceutical development are capable of enhancing the local
delivery of cytotoxic drugs. The ability to conjugate different targeting ligands to the …

[图书][B] Dendrimer-based nanotherapeutics

P Kesharwani - 2021 - books.google.com
Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of
dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine …

Dendrimer toxicity: Let's meet the challenge

K Jain, P Kesharwani, U Gupta, NK Jain - International journal of …, 2010 - Elsevier
Dendrimers are well-defined, versatile polymeric architecture with properties resembling
biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine …

Dendrimers as pharmaceutical excipients: synthesis, properties, toxicity and biomedical applications

A Santos, F Veiga, A Figueiras - Materials, 2019 - mdpi.com
The European Medicines Agency (EMA) and the Current Good Manufacturing Practices
(cGMP) in the United States of America, define excipient as the constituents of the …