For rapid response against the prevailing COVID‐19 (coronavirus disease 19), it is a global
imperative to exploit the immunogenicity of existing formulations for safe and efficient …

There is a need for additional rapidly scalable, low-cost vaccines against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) to achieve global vaccination. Aluminum …

Aluminum salts, developed almost a century ago, remain the most commonly used adjuvant
for licensed human vaccines. Compared to more recently developed vaccine adjuvants …

Particulate adjuvants have been successful at inducing increased immune responses
against many poorly immunogenic antigens. However, the mechanism of action of these …

Aluminum-salt-based vaccine adjuvants are prevailingly used in FDA-approved vaccines for
the prevention of infectious diseases for over eighty years. Despite their safe applications …

Due to its safety and efficacy, aluminum hydroxide is used as an immune adjuvant in human
vaccines for over 80 years. Being a Th2 stimulator, the classical gel‐like adjuvant, however …

The COVID-19 pandemic continues to spread worldwide. To protect and control the spread
of SARS-CoV-2, varieties of subunit vaccines based on spike (S) proteins have been …

Aluminum hydroxide is used as a vaccine adjuvant in various human vaccines.
Unfortunately, despite its favorable safety profile, aluminum hydroxide can only weakly or …

Developing a novel and potent adjuvant with great biocompatibility for immune response
augmentation is of great significance to enhance vaccine efficacy. In this work, we prepared …

Aluminium (Al) compounds are used as adjuvants in human and veterinary prophylactic
vaccines due to their improved tolerability compared to other adjuvants. These Al-based …