High-sensitivity C-reactive protein, low-grade systemic inflammation and type 2 diabetes mellitus: a two-sample Mendelian randomization study

R Noordam, CH Oudt, MM Bos, RAJ Smit… - Nutrition, Metabolism …, 2018 - Elsevier
Background and aims The role of inflammation in type 2 diabetes mellitus (T2D) remains
unclear. We investigated the associations of high sensitivity C-reactive protein (hsCRP) …

[HTML][HTML] Exposing the causal effect of C-reactive protein on the risk of type 2 diabetes mellitus: a Mendelian randomization study

L Cheng, H Zhuang, S Yang, H Jiang, S Wang… - Frontiers in …, 2018 - frontiersin.org
As a biomarker of inflammation, C-reactive protein (CRP) has attracted much attention due
to its role in the incidence of type 2 diabetes mellitus (T2DM). Prospective studies have …

C-reactive protein gene variation and type 2 diabetes mellitus: A case–control study

RYL Zee, S Germer, A Thomas, A Raji, B Rhees… - Atherosclerosis, 2008 - Elsevier
OBJECTIVE: C-reactive protein (CRP) gene variation, in particular an rs2794521 variant
was recently associated with type 2 diabetes mellitus (T2DM) in Pima Indians. RESEARCH …

[HTML][HTML] Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream

EJ Brunner, M Kivimäki, DR Witte, DA Lawlor… - PLoS …, 2008 - journals.plos.org
Background Raised C-reactive protein (CRP) is a risk factor for type 2 diabetes. According to
the Mendelian randomization method, the association is likely to be causal if genetic …

[HTML][HTML] Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree

H Uemura, AA Ghaibeh, S Katsuura-Kamano… - Scientific reports, 2017 - nature.com
To investigate unknown patterns associated with type 2 diabetes in the Japanese
population, we first used an alternating decision tree (ADTree) algorithm, a powerful …

High‐sensitivity C‐reactive protein and risk of type 2 diabetes: a nationwide cohort study and updated meta‐analysis

X Yang, S Tao, J Peng, J Zhao, S Li… - Diabetes/metabolism …, 2021 - Wiley Online Library
Objective To prospectively examine the association of high sensitivity C‐reactive protein (hs‐
CRP) with incident type 2 diabetes mellitus (T2DM) among middle‐aged and elderly …

Genetic variation, C-reactive protein levels, and incidence of diabetes

A Dehghan, I Kardys, MPM de Maat, AG Uitterlinden… - …, 2007 - Am Diabetes Assoc
C-reactive protein (CRP) has been shown to be associated with type 2 diabetes, but whether
CRP has a causal role is not yet clear. We examined the association in the Rotterdam Study …

High-sensitivity C-reactive protein levels and type 2 diabetes in urban North Indians

A Mahajan, R Tabassum, S Chavali… - The Journal of …, 2009 - academic.oup.com
Context: Elevated high-sensitivity C-reactive protein (hsCRP) levels have frequently been
shown to be associated with type 2 diabetes (T2D); however, very little is known about this in …

[HTML][HTML] A linear positive association between high-sensitivity C-reactive protein and the prevalence of cardiovascular disease among individuals with diabetes

Y Liu, W He, Y Ji, Q Wang, X Li - BMC Cardiovascular Disorders, 2024 - Springer
Aims To assess the correlation between high-sensitivity C-reactive protein (Hs-CRP) and the
prevalence of cardiovascular disease (CVD) among individuals with diabetes. Methods A …

[HTML][HTML] Temporal relationship between inflammation and insulin resistance and their joint effect on hyperglycemia: the Bogalusa Heart Study

Y Yan, S Li, Y Liu, L Bazzano, J He, J Mi… - Cardiovascular …, 2019 - Springer
Background Inflammation and insulin resistance play crucial roles in the development of
type 2 diabetes mellitus (T2DM). We aim to examine the temporal relationship between high …