[PDF][PDF] Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
A Marsee, FJM Roos, MMA Verstegen, F Roos… - Cell Stem Cell, 2021 - cell.com
Hepatic, pancreatic, and biliary (HPB) organoids are powerful tools for studying
development, disease, and regeneration. As organoid research expands, the need for clear …
development, disease, and regeneration. As organoid research expands, the need for clear …
[HTML][HTML] Next-generation liver medicine using organoid models
“Liver medicine” refers to all diagnostic and treatment strategies of diseases and conditions
that cause liver failure directly or indirectly. Despite significant advances in the field of liver …
that cause liver failure directly or indirectly. Despite significant advances in the field of liver …
Concise review: organoids are a powerful tool for the study of liver disease and personalized treatment design in humans and animals
S Nantasanti, A de Bruin, J Rothuizen… - Stem cells …, 2016 - academic.oup.com
Organoids are three-dimensional culture systems in which adult stem cells and their
progeny grow and represent the native physiology of the cells in vivo. Organoids have been …
progeny grow and represent the native physiology of the cells in vivo. Organoids have been …
Hepatobiliary organoids and their applications for studies of liver health and disease: are we there yet?
Organoid culture systems have emerged as a frontier technology in liver and biliary
research. These three‐dimensional (3D) cell cultures derived from pluripotent and adult …
research. These three‐dimensional (3D) cell cultures derived from pluripotent and adult …
Liver organoids: from basic research to therapeutic applications
Organoid cultures have emerged as an alternative in vitro system to recapitulate tissues in a
dish. While mouse models and cell lines have furthered our understanding of liver biology …
dish. While mouse models and cell lines have furthered our understanding of liver biology …
[HTML][HTML] Organoids to model liver disease
S Nuciforo, MH Heim - JHEP Reports, 2021 - Elsevier
The organoid model represents a major breakthrough in cell biology that has revolutionised
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …
Liver organoids: recent developments, limitations and potential
SP Harrison, SF Baumgarten, R Verma, O Lunov… - Frontiers in …, 2021 - frontiersin.org
Liver cell types derived from induced pluripotent stem cells (iPSCs) share the potential to
investigate development, toxicity, as well as genetic and infectious disease in ways currently …
investigate development, toxicity, as well as genetic and infectious disease in ways currently …
Generation of expandable human pluripotent stem cell-derived hepatocyte-like liver organoids
SJ Mun, JS Ryu, MO Lee, YS Son, SJ Oh, HS Cho… - Journal of …, 2019 - Elsevier
Background & Aims The development of hepatic models capable of long-term expansion
with competent liver functionality is technically challenging in a personalized setting. Stem …
with competent liver functionality is technically challenging in a personalized setting. Stem …
Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering?
Adult tissue stem cells can form self-organizing 3D organoids in vitro. Organoids resemble
small units of their organ of origin and have great potential for tissue engineering, as well as …
small units of their organ of origin and have great potential for tissue engineering, as well as …
Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells
Human organoids are emerging as a valuable resource to investigate human organ
development and disease. The applicability of human organoids has been limited, partly …
development and disease. The applicability of human organoids has been limited, partly …