Increased risk of aging-related neurodegenerative disease after traumatic brain injury

S Barker, BD Paul, AA Pieper - Biomedicines, 2023 - mdpi.com
Traumatic brain injury (TBI) survivors frequently suffer from chronically progressive
complications, including significantly increased risk of developing aging-related …

Alzheimer's disease-related dementias summit 2019: National Research Priorities for the investigation of traumatic brain injury as a risk factor for Alzheimer's disease …

K Dams-O'Connor, PSF Bellgowan… - Journal of …, 2021 - liebertpub.com
Traumatic brain injury (TBI) is a risk factor for later-life dementia. Clinical and pre-clinical
studies have elucidated multiple mechanisms through which TBI may influence or …

Alzheimer's Disease-Related Dementias Summit 2022: national research priorities for the investigation of post-traumatic brain injury Alzheimer's disease and related …

K Dams-O'Connor, HO Awwad, S Hoffman… - Journal of …, 2023 - liebertpub.com
Traumatic Brain Injury (TBI) is a risk factor for Alzheimer's disease and Alzheimer's disease
related dementias (AD/ADRD) and otherwise classified post-traumatic neurodegeneration …

Traumatic brain injury: a risk factor for neurodegenerative diseases

R Gupta, N Sen - Reviews in the Neurosciences, 2016 - degruyter.com
Traumatic brain injury (TBI), a major global health and socioeconomic problem, is now
established as a chronic disease process with a broad spectrum of pathophysiological …

Multimodal characterization of the late effects of traumatic brain injury: a methodological overview of the late effects of traumatic brain injury project

BL Edlow, CD Keene, DP Perl, D Iacono… - Journal of …, 2018 - liebertpub.com
Epidemiological studies suggest that a single moderate-to-severe traumatic brain injury
(TBI) is associated with an increased risk of neurodegenerative disease, including …

Traumatic brain injury and secondary neurodegenerative disease

WS Dodd, EJ Panther, K Pierre, JS Hernandez, D Patel… - Trauma Care, 2022 - mdpi.com
Traumatic brain injury (TBI) is a devastating event with severe long-term complications. TBI
and its sequelae are one of the leading causes of death and disability in those under 50 …

The emergence of model systems to investigate the link between traumatic brain injury and Alzheimer's disease

G Srinivasan, DA Brafman - Frontiers in aging neuroscience, 2022 - frontiersin.org
Numerous epidemiological studies have demonstrated that individuals who have sustained
a traumatic brain injury (TBI) have an elevated risk for developing Alzheimer's disease and …

Traumatic brain injury and risk of neurodegenerative disorder

BL Brett, RC Gardner, J Godbout, K Dams-O'Connor… - Biological …, 2022 - Elsevier
Traumatic brain injury (TBI), particularly of greater severity (ie, moderate to severe), has
been identified as a risk factor for all-cause dementia and Parkinson's disease, with risk for …

Traumatic brain injury as a risk factor for Alzheimer's disease: current knowledge and future directions

K Dams-O'Connor, G Guetta… - Neurodegenerative …, 2016 - Taylor & Francis
There is growing concern about the late effects of traumatic brain injury (TBI). This scoping
review summarizes clinical research from the past 10 years that evaluates the relationship …

An update on the association between traumatic brain injury and Alzheimer's disease: Focus on Tau pathology and synaptic dysfunction

L Li, J Liang, H Fu - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Abstract LP Li, JW Liang and HJ Fu. An update on the association between traumatic brain
injury and Alzheimer's disease: Focus on Tau pathology and synaptic dysfunction …