Circadian rhythms occur in almost all species and control vital aspects of our physiology,
from sleeping and waking to neurotransmitter secretion and cellular metabolism …

Obesity has become a serious public health problem and a major risk factor for the
development of illnesses, such as insulin resistance and hypertension. Human homeostatic …

Recent advances in the understanding of the molecular, genetic, neural, and physiologic
basis for the generation and organization of circadian clocks in mammals have revealed …

Circadian rhythms occur with a periodicity of approximately 24h and regulate a wide array of
metabolic and physiologic functions. Accumulating epidemiological and genetic evidence …

The discovery of the genetic basis for circadian rhythms has expanded our knowledge of the
temporal organization of behavior and physiology. The observations that the circadian gene …

Mammals have developed an endogenous circadian clock located in the SCN
(suprachiasmatic nuclei) of the anterior hypothalamus that responds to the environmental …

Most organisms adapt to the 24-h cycle of the Earth's rotation by anticipating the time of the
day through light-dark cycles. The internal time-keeping system of the circadian clocks has …

Circadian rhythms evolved through adaptation to daily light/dark changes in the
environment; they are believed to be regulated by the core circadian clock interlocking …

Circadian clocks maintain periodicity in internal cycles of behavior, physiology, and
metabolism, enabling organisms to anticipate the 24-h rotation of the Earth. In mammals …

The circadian clock programs daily rhythms and coordinates multiple behavioral and
physiological processes, including activity, sleep, feeding, and fuel homeostasis. Recent …