Molecular signature of active fibrogenesis prevails in biliary atresia after successful portoenterostomy
A Kerola, H Lampela, J Lohi, P Heikkilä, A Mutanen… - Surgery, 2017 - Elsevier
Background In biliary atresia mechanisms of progressive liver injury leading to need of liver
transplantation after successful portoenterostomy remain unknown. A better understanding …
transplantation after successful portoenterostomy remain unknown. A better understanding …
Liver fibrosis in biliary atresia
AB Haafiz - Expert review of gastroenterology & hepatology, 2010 - Taylor & Francis
Biliary atresia (BA) is the most common cholestatic liver disorder requiring liver
transplantation in children. Hepatic fibrosis is not only a universal and prominent feature of …
transplantation in children. Hepatic fibrosis is not only a universal and prominent feature of …
[PDF][PDF] Evolving Up‐regulation of Biliary Fibrosis–Related Extracellular Matrix Molecules After Successful Portoenterostomy
A Kyrönlahti, N Godbole, O Akinrinade… - Hepatology …, 2021 - Wiley Online Library
Successful portoenterostomy (SPE) improves the short‐term outcome of patients with biliary
atresia (BA) by relieving cholestasis and extending survival with native liver. Despite SPE …
atresia (BA) by relieving cholestasis and extending survival with native liver. Despite SPE …
Native liver histology after successful portoenterostomy in biliary atresia
H Lampela, S Kosola, P Heikkilä, J Lohi… - Journal of clinical …, 2014 - journals.lww.com
Background: Biliary atresia is the most common indication for childhood liver transplantation.
The effects of successful portoenterostomy (PE) on native liver histology remain unclear …
The effects of successful portoenterostomy (PE) on native liver histology remain unclear …
Divergent expression of liver transforming growth factor superfamily cytokines after successful portoenterostomy in biliary atresia
A Kerola, J Lohi, P Heikkilä, A Mutanen, H Jalanko… - Surgery, 2019 - Elsevier
Background Pathogenesis of progressive liver fibrosis in biliary atresia after successful
portoenterostomy remains unclear. We related hepatic expression of transforming growth …
portoenterostomy remains unclear. We related hepatic expression of transforming growth …
Outcome after portoenterostomy in biliary atresia: pivotal role of degree of liver fibrosis and intensity of stellate cell activation
E Shteyer, GA Ramm, C Xu, FV White… - Journal of pediatric …, 2006 - journals.lww.com
Objectives: Biliary atresia (BA), a congenital idiopathic obliterative cholangiopathy, rapidly
leads to liver cirrhosis and liver failure if untreated. A timely Kasai portoenterostomy (KP) …
leads to liver cirrhosis and liver failure if untreated. A timely Kasai portoenterostomy (KP) …
Increased MMP‐7 expression in biliary epithelium and serum underpins native liver fibrosis after successful portoenterostomy in biliary atresia
A Kerola, H Lampela, J Lohi, P Heikkilä… - The Journal of …, 2016 - Wiley Online Library
The molecular mechanisms underlying progressive liver fibrosis following surgical treatment
of biliary atresia (BA) remain unclear. Our aim was to address hepatic gene and protein …
of biliary atresia (BA) remain unclear. Our aim was to address hepatic gene and protein …
The extent of biliary proliferation in liver biopsies from patients with biliary atresia at portoenterostomy is associated with the postoperative prognosis
JL Santos, CO Kieling, L Meurer, S Vieira… - Journal of Pediatric …, 2009 - Elsevier
BACKGROUND/PURPOSE: In biliary atresia (BA), a derangement in the biliary system
remains, despite portoenterostomy performance. Many factors can influence the disease …
remains, despite portoenterostomy performance. Many factors can influence the disease …
[HTML][HTML] Temporal histopathological changes in biliary atresia: a perspective for rapid fibrosis progression
HA El-Araby, MA Saber, NM Radwan, DM Taie… - Annals of hepatology, 2021 - Elsevier
Abstract Introduction and Objectives Biliary atresia (BA) is characterized by rapid
progression of fibrosis with no definite causes. Histopathological findings have been …
progression of fibrosis with no definite causes. Histopathological findings have been …
Contribution of hepatic parenchymal and nonparenchymal cells to hepatic fibrogenesis in biliary atresia
GA Ramm, VG Nair, KR Bridle, RW Shepherd… - The American journal of …, 1998 - Elsevier
Extrahepatic biliary atresia is a severe neonatal liver disease resulting from a sclerosing
cholangiopathy of unknown etiology. Although biliary obstruction may be surgically …
cholangiopathy of unknown etiology. Although biliary obstruction may be surgically …
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